Gene Symbol | DDX25 |
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Entrez Gene | 29118 |
Alt Symbol | GRTH |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box helicase 25 |
Other Description | ATP-dependent RNA helicase DDX25|DEAD (Asp-Glu-Ala-Asp) box polypeptide 25|DEAD box protein 25|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 25|gonadotropin-regulated testicular RNA helicase |
Swissprots | Q86W81 Q5XVN2 Q9UHL0 Q8IYP1 B2R6Z0 |
Accessions | AAU84667 ABW87006 ABW87007 ACA64098 EAW67668 EAW67669 Q9UHL0 AF155140 AAF21371 AK295121 BAG58148 AK312772 BAG35637 BC031098 BC035388 AAH35388 BC050360 AAH50360 CD359894 CD657404 DC395868 XM_011542790 XP_011541092 XM_011542791 XP_011541093 NM_013264 NP_037396 |
Function | ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10608860}. Nucleus {ECO:0000250}. Note=Detected in both cytoplasm and nucleus of testicular cells. Also detected in chromatoid bodies of round spermatids (By similarity). {ECO:0000250}. |
Tissue Specificity | Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus. {ECO:0000269|PubMed:10608860, ECO:0000269|Ref.2}. |
DDX25 CRISPR/Cas9 KO Plasmid (h) - sc-406132 from Santa Cruz Biotechnology
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DDX25 HDR Plasmid (h) - sc-406132-HDR from Santa Cruz Biotechnology
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DDX25 Double Nickase Plasmid (h) - sc-406132-NIC from Santa Cruz Biotechnology
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DDX25 Double Nickase Plasmid (h2) - sc-406132-NIC-2 from Santa Cruz Biotechnology
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DDX25 CRISPR Activation Plasmid (h) - sc-406132-ACT from Santa Cruz Biotechnology
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DDX25 CRISPR Activation Plasmid (h2) - sc-406132-ACT-2 from Santa Cruz Biotechnology
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DDX25 Lentiviral Activation Particles (h) - sc-406132-LAC from Santa Cruz Biotechnology
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DDX25 Lentiviral Activation Particles (h2) - sc-406132-LAC-2 from Santa Cruz Biotechnology
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DDX25 siRNA (h) - sc-72229 from Santa Cruz Biotechnology
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DDX25 shRNA Plasmid (h) - sc-72229-SH from Santa Cruz Biotechnology
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DDX25 shRNA (h) Lentiviral Particles - sc-72229-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU039751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7048 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7048 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01237 from Sigma-Aldrich
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DDX25 siRNA (Human) - CRH9207 from Cohesion Biosciences
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DDX25 - MBS8220831 from MyBioSource
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shRNA set against Human DDX25 (NM_013264.4) - SHH275913 from Creative biogene
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Human DDX25 siRNA - orb269709 from Biorbyt
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DDX25 shRNA Plasmid (Human) - CHH9207 from Cohesion Biosciences
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DDX25 miRNA 3'UTR clone - MiUTR3H-09374 from Creative biogene
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