CNIH2

Gene Symbol CNIH2
Entrez Gene 254263
Alt Symbol CNIH-2, Cnil
Species Human
Gene Type protein-coding
Description cornichon family AMPA receptor auxiliary protein 2
Other Description cornichon homolog 2|protein cornichon homolog 2
Swissprots Q6PI25
Accessions EAW74508 Q6PI25 AI928591 AY726585 BC047953 AAH47953 BC160083 AAI60083 BM547951 DR760677 HQ448517 ADQ32996 NM_182553 NP_872359 NR_073078 NR_073079
Function Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. {ECO:0000269|PubMed:20805473}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). {ECO:0000250}.
Tissue Specificity Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). {ECO:0000269|PubMed:23103966}.

Human Protein cornichon homolog 2 full length protein - ab166032 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166032 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CNIH2 Antibody Blocking Peptide - LS-E1047 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CNIH2 Antibody Blocking Peptide - LS-E24542 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CNIH2 Protein - H00254263-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CNIH2-Antibody-N-term-Blocking-peptide - BP11529a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Cornichon homolog 2 - H00254263-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Cornichon homolog 2 - H00254263-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CNIH2 fusion protein - Ag5533 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

CNIH2 fusion protein - ag15074 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human CNIH2, GST-tagged - CNIH2-11380H from Creative Biomart

Category Protein
Source E.coli
Species Human

Cornichon homolog 2 - TP315357 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Cornichon homolog 2

CNIH2 Peptide, Human - M34GP03364H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protein cornichon homolog 2 (CNIH2), Recombinant Protein - MBS7011871 from MyBioSource

Category Protein
Prices $985.00, $1,965.00, $3,175.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human
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