| Gene Symbol |
ZG16
|
| Entrez Gene |
653808
|
| Alt Symbol |
JCLN, JCLN1, ZG16A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zymogen granule protein 16
|
| Other Description |
jacalin-like lectin domain containing|secretory lectin ZG16|zymogen granule membrane protein 16|zymogen granule protein 16 homolog
|
| Swissprots |
B9EK72 O60844 B2R4Z3
|
| Accessions |
AAC08708 EAW80011 O60844 AB092813 BAC20361 AK125559 BAG54214 AK312002 BAG34940 BC029149 AAH29149 BC150656 AAI50657 CK904265 DQ890795 ABM81721 DQ893950 ABM84876 XM_011545921 XP_011544223 NM_152338 NP_689551
|
| Function |
May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. {ECO:0000269|PubMed:17307141}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17307141}. Cytoplasmic vesicle lumen {ECO:0000305|PubMed:17307141}. Golgi apparatus lumen {ECO:0000269|PubMed:17307141}. Note=Stored in zymogen granules. {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in liver. Detected at lower levels in colon, ileum and jejunum. {ECO:0000269|PubMed:17307141}.
|
![Western Blot: ZG16 Overexpression Lysate (Adult Normal) [NBL1-18030] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZG16.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7211_ZG16%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-18030-img0002.jpg)