Gene Symbol |
ZG16
|
Entrez Gene |
653808
|
Alt Symbol |
JCLN, JCLN1, ZG16A
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zymogen granule protein 16
|
Other Description |
jacalin-like lectin domain containing|secretory lectin ZG16|zymogen granule membrane protein 16|zymogen granule protein 16 homolog
|
Swissprots |
B9EK72 O60844 B2R4Z3
|
Accessions |
AAC08708 EAW80011 O60844 AB092813 BAC20361 AK125559 BAG54214 AK312002 BAG34940 BC029149 AAH29149 BC150656 AAI50657 CK904265 DQ890795 ABM81721 DQ893950 ABM84876 XM_011545921 XP_011544223 NM_152338 NP_689551
|
Function |
May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. {ECO:0000269|PubMed:17307141}.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17307141}. Cytoplasmic vesicle lumen {ECO:0000305|PubMed:17307141}. Golgi apparatus lumen {ECO:0000269|PubMed:17307141}. Note=Stored in zymogen granules. {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in liver. Detected at lower levels in colon, ileum and jejunum. {ECO:0000269|PubMed:17307141}.
|