Gene Symbol | ZG16 |
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Entrez Gene | 653808 |
Alt Symbol | JCLN, JCLN1, ZG16A |
Species | Human |
Gene Type | protein-coding |
Description | zymogen granule protein 16 |
Other Description | jacalin-like lectin domain containing|secretory lectin ZG16|zymogen granule membrane protein 16|zymogen granule protein 16 homolog |
Swissprots | B9EK72 O60844 B2R4Z3 |
Accessions | AAC08708 EAW80011 O60844 AB092813 BAC20361 AK125559 BAG54214 AK312002 BAG34940 BC029149 AAH29149 BC150656 AAI50657 CK904265 DQ890795 ABM81721 DQ893950 ABM84876 XM_011545921 XP_011544223 NM_152338 NP_689551 |
Function | May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN. {ECO:0000269|PubMed:17307141}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:17307141}. Cytoplasmic vesicle lumen {ECO:0000305|PubMed:17307141}. Golgi apparatus lumen {ECO:0000269|PubMed:17307141}. Note=Stored in zymogen granules. {ECO:0000250}. |
Tissue Specificity | Highly expressed in liver. Detected at lower levels in colon, ileum and jejunum. {ECO:0000269|PubMed:17307141}. |
ZG16 CRISPR/Cas9 KO Plasmid (h) - sc-416162 from Santa Cruz Biotechnology
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ZG16 HDR Plasmid (h) - sc-416162-HDR from Santa Cruz Biotechnology
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ZG16 Double Nickase Plasmid (h) - sc-416162-NIC from Santa Cruz Biotechnology
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ZG16 Double Nickase Plasmid (h2) - sc-416162-NIC-2 from Santa Cruz Biotechnology
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ZG16 CRISPR Activation Plasmid (h) - sc-416162-ACT from Santa Cruz Biotechnology
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ZG16 CRISPR Activation Plasmid (h2) - sc-416162-ACT-2 from Santa Cruz Biotechnology
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ZG16 Lentiviral Activation Particles (h) - sc-416162-LAC from Santa Cruz Biotechnology
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ZG16 Lentiviral Activation Particles (h2) - sc-416162-LAC-2 from Santa Cruz Biotechnology
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ZG16 siRNA (h) - sc-93222 from Santa Cruz Biotechnology
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ZG16 shRNA Plasmid (h) - sc-93222-SH from Santa Cruz Biotechnology
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ZG16 shRNA (h) Lentiviral Particles - sc-93222-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN23211 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23211 from Sigma-Aldrich
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ZG16 siRNA (Human) - CRJ8604 from Cohesion Biosciences
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ZG16 - MBS829587 from MyBioSource
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shRNA set against Human ZG16 (NM_152338.3) - SHH452552 from Creative biogene
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Human ZG16 siRNA - orb279105 from Biorbyt
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ZG16 shRNA Plasmid (Human) - CHJ8604 from Cohesion Biosciences
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ZG16 miRNA 3'UTR clone - MiUTR3H-15177 from Creative biogene
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