| Gene Symbol |
ATP5H
|
| Entrez Gene |
10476
|
| Alt Symbol |
ATPQ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
|
| Other Description |
ATP synthase D chain, mitochondrial|ATP synthase subunit d, mitochondrial|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d|ATP synthase, H+ transporting, mitochondrial F1F0, subunit d|ATPase subunit d|My032 protein
|
| Swissprots |
Q9H3J4 O75947 B2R5L6
|
| Accessions |
EAW89228 EAW89229 O75947 AA608885 AF061735 AAG43146 AF070650 AAD20956 AF086159 AF087135 AAC36338 AK095671 AK312230 BAG35163 BC029392 AAH29392 BC032245 AAH32245 BC038092 AAH38092 DQ583597 NM_001003785 NP_001003785 NM_006356 NP_006347
|
| Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
|
| Subcellular Location |
Mitochondrion. Mitochondrion inner membrane.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Oxidative phosphorylation
|