NR2C2

Gene Symbol	NR2C2
Entrez Gene	7182
Alt Symbol	TAK1, TR4
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group C, member 2
Other Description	Nuclear hormone receptor TR4|nuclear receptor subfamily 2 group C member 2|orphan nuclear receptor TAK1|orphan nuclear receptor TR4|testicular nuclear receptor 4
Swissprots	A8K3H5 P55092 P49116 B6ZGT8
Accessions	AAC50672 AAC50673 AAC50675 AAC50676 EAW64213 EAW64214 EAW64215 P49116 AB307708 BAH02299 AI986459 AK091226 AK094590 AK290590 BAF83279 BC030715 BC051670 AAH51670 BF307171 CA430806 HQ995528 ADZ31973 L27586 AAA21474 XM_011534058 XP_011532360 XM_011534059 XP_011532361 XM_011534060 XP_011532362 XM_011534061 XP_011532363 XM_011534062 XP_011532364 XM_011534063 XP_011532365 XM_011534064 XP_011532366 XM_011534065 XP_011532367 XM_011534066 XP_011532368 NM_001291694 NP_001278623 NM_003298 NP_003289
Function	Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation. {ECO:0000250, ECO:0000269|PubMed:10347174, ECO:00
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:10644740}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NR2C2 full length protein - ab152762 from Abcam Category Protein Source Wheat germ Species Human

Human NR2C2 protein fragment - ab152763 from Abcam Category Protein Source Wheat germ Species Human

NR2C2 / TAK1 Antibody Blocking Peptide - LS-E13755 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C2 / TAK1 Antibody Blocking Peptide - LS-E16648 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C2 / TAK1 Antibody Blocking Peptide - LS-E6557 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TR4/NR2C2 Protein - H00007182-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TR4/NR2C2 Protein - H00007182-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

NR2C2-Antibody-C-term-Blocking-Peptide - BP19331b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant human Nuclear receptor subfamily 2 group C member 2 protein (OPCA01096) - OPCA01096 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

NR2C2 Blocking Peptide - 33R-4073 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR2C2 Blocking Peptide - 33R-1445 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NR2C2 - H00007182-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

NR2C2 - H00007182-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NR2C2 - H00007182-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human Nuclear receptor subfamily 2 group C member 2(NR2C2) - CSB-YP016052HU CSB-EP016052HU CSB-BP016052HU CSB-MP016052HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Nuclear receptor subfamily 2 group C member 2 protein - RPC140945 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

NR2C2 - TP319184 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TR4/NR2C2 Recombinant Protein Antigen - NBP1-81658PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NR2C2 Peptide, Human - M34GP10593H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nuclear receptor subfamily 2 group C member 2 (NR2C2), Recombinant Protein - MBS949282 from MyBioSource Category Protein Prices $1,395.00, $1,395.00, $1,615.00, $1,615.00, $2,335.00, $2,335.00, $2,780.00, $2,780.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Testicular Receptor 4, Recombinant Protein - MBS2034582 from MyBioSource Category Protein Prices $175.00, $360.00, $560.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Human

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