RHOB

Gene Symbol RHOB
Entrez Gene 388
Alt Symbol ARH6, ARHB, MST081, MSTP081, RHOH6
Species Human
Gene Type protein-coding
Description ras homolog family member B
Other Description Aplysia RAS-related homolog 6|h6|oncogene RHO H6|ras homolog gene family, member B|rho cDNA clone 6|rho-related GTP-binding protein RhoB
Swissprots Q9CUV7 Q5U0H6 P01121 B2R692 Q7RTR9 P62745 Q7RTN5
Accessions AAY24345 DAA01912 EAX00819 EAX00820 P62745 AF171089 AAQ13605 AF498971 AAM21118 AK124398 BAG54035 AK309991 AK310813 AK312487 BAG35389 BC062781 BC066954 AAH66954 BK001232 DAA01138 BM669284 BT019546 AAV38353 BT019547 AAV38354 CA443347 CR542272 CAG47068 EU832788 ACE87799 GQ129351 ACT64485 M12174 AAA36565 X06820 CAA29968 NM_004040 NP_004031
Function Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. {ECO:0000269|PubMed:10508588, ECO:0000269|PubMed:15226397, ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:21373644, ECO:0000269|PubMed:9478917}.
Subcellular Location Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus. Cleavage furrow. Note=Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.

RhoB Antibody - 2098 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and rat brain tissue using RhoB Antibody.

Rho B (A-15) - sc-32042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rho B (A-15): sc-32042. Western blot analysis of Rho B expression in non-transfected: sc-117752 (A) and human Rho B transfected: sc-177862 (B) 293T whole cell lysates.

Rho B (119) - sc-180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rho B (119): sc-180. Western blot analysis of Rho B expression in lysates from UV-treated HeLa cells.

Rho B (C-5) - sc-8048 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Rho B (C-5): sc-8048. Western blot analysis of Rho B expression in HeLa whole cell ysate.

Rho B (M-19) - sc-21322 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rho B (M-19): sc-21322. Western blot analysis of Rho B expression in non-transfected: sc-117752 (A) and human Rho B transfected: sc-177862 (B) 293T whole cell lysates.

Anti-RHOB antibody - ab68827 from Abcam

Host Rabbit
Clonality Polyclonal
IF on 1 day old mouse cortical cell culture using ab68827 at 1: 2000 dilution. DAPI counter stained.

Anti-RHOB antibody - ab75064 from Abcam

Host Sheep
Clonality Polyclonal

Anti-RHOB antibody - ab170611 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling RHOB with ab170611 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-RHOB antibody - ab138035 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RHOB antibody (ab138035) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-RHOB antibody [2916C2a] - ab53743 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2916C2a
Anti-RHOB antibody [2916C2a] (ab53743) + immunized recombinant protein

Anti-RHOB Antibody - LS-C75452 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-RHOB Antibody - LS-C94745 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-RHOB Antibody - LS-C94747 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-RHOB Antibody (clone 2916C2a) - LS-C184468 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2916C2a

Anti-RHOB Antibody (aa99-148) - LS-C291377 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RHOB Antibody (aa82-131) - LS-C200600 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using RHOB antibody.

Anti-RHOB Antibody (clone 2916C2a) - LS-C342509 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2916C2a
Western blot analysis of immunized recombinant protein, using anti-RHOB monoclonal antibody.

Anti-RHOB Antibody - LS-C330988 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain tissue, using RhoB antibody.

Anti-RHOB Antibody (aa104-137) - LS-C156463 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARHB Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RHOB Antibody (aa107-156) IHC-plus™ - LS-B11954 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

RhoB Antibody - NBP2-20154 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RhoB Antibody - NBP1-03484 from Novus Biologicals

Prices $299.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

RhoB Antibody - NB100-91274 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: RhoB Antibody [NB100-91274] - 1 day- old mouse cortical cell culture using Rabbit antibody to Rho-related GTP-binding protein RhoB: whole serum at 1:2000 dilution. DAPI counter stained.

RhoB Antibody - H00000388-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RhoB Antibody [H00000388-D01P] - Analysis of RHOB expression in transfected 293T cell line by RHOB polyclonal antibody.Lane 1: RHOB transfected lysate(22.10 KDa).Lane 2: Non-transfected lysate.

Rabbit Anti-Rho B Polyclonal Antibody - bs-11142R from Bioss

Host Rabbit
Clonality Polyclonal
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