SYNCRIP

Gene Symbol	SYNCRIP
Entrez Gene	10492
Alt Symbol	GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q
Species	Human
Gene Type	protein-coding
Description	synaptotagmin binding, cytoplasmic RNA interacting protein
Other Description	NS1-associated protein 1\|glycine- and tyrosine-rich RNA-binding protein\|heterogeneous nuclear ribonucleoprotein Q
Swissprots	Q96LC2 E1P502 Q5TCG2 Q8N599 Q9Y583 Q5TCG3 Q53H05 Q96LC1 O60506 E1P501 Q8IW78
Accessions	EAW48622 EAW48623 EAW48624 EAW48625 EAW48626 EAW48627 EAW48628 EAW48629 EAW48630 O60506 AA411631 AB209098 BAD92335 AF037448 AAC12926 AF155568 AAD38198 AK056188 AK222776 BAD96496 AK294212 BAH11699 AK299796 BAH13131 AK313572 BAG36345 AY034481 AAK59703 AY034482 AAK59704 AY034483 AAK59705 BC009176 BC015575 AAH15575 BC021932 BC024283 AAH24283 BC032643 AAH32643 BC040844 AAH40844 BF221524 CV806885 DA117533 DA845413 DB160837 JF432810 ADZ16027 XM_005248635 XP_005248692 XM_005248636 XP_005248693 XM_005248637 XP_005248694 NM_001159673 NP_001153145 NM_001159674 NP_001153146 NM_001159675 NP_001153147 NM_001159676 NP_001153148 NM_001159677 NP_001153149 NM_001253771 NP_001240700 NM_006372 NP_006363
Function	Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD- mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with s
Subcellular Location	Isoform 2: Nucleus, nucleoplasm {ECO:0000250}. Note=Expressed predominantly in the nucleoplasm. {ECO:0000250}.
Tissue Specificity	Ubiquitously expressed. Detected in heart, brain, pancreas, placenta, spleen, lung, liver, skeletal muscle, kidney, thymus, prostate, uterus, small intestine, colon, peripheral blood and testis. {ECO:0000269\|PubMed:11352648}.

hnRNP Q/R (D18B2) Rabbit mAb - 8588 from Cell Signaling Technology

Prices	$246.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Monoclonal
Clone	D18B2

Western blot analysis of extracts from SW620 and HCT 116 cells using hnRNP Q/R (D18B2) Rabbit mAb.

hnRNP Q/R Antibody - 5351 from Cell Signaling Technology

Prices	$246.00
Sizes	100 µl (10 western blots)
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts from HeLa and HT-29 cells using hnRNP Q/R Antibody.

hnRNP Q (I8E4) - sc-56703 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

hnRNP Q (I8E4): sc-56703. Western blot analysis of hnRNP Q expression in A549 (A) and WI 38 (B) whole cell lysates.

hnRNP Q (Y-13) - sc-69572 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

hnRNP Q (Y-13): sc-69572. Western blot analysis of hnRNP Q expression in A549 whole cell lysate.

Anti-hnRNP Q antibody - ab189405 from Abcam

Prices	$384.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons, tissue labeling hnRNP Q with ab189405 at 20 µg/ml.

Anti-hnRNP Q antibody - ab199417 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-hnRNP Q antibody (ab199417) at 1/1000 dilutionLane 1 : HT29 cell line lysateLane 2 : Hela cell line lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L (HRP) at 1/5000 dilution

Anti-hnRNP Q antibody - ab99152 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-hnRNP Q antibody (ab99152) at 1 µg/ml + HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate at 20 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-hnRNP Q antibody - ab58854 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-hnRNP Q antibody (ab58854) at 1.25 µg/ml + HepG2 cell lysate at 10µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-hnRNP Q antibody - ab103135 from Abcam

Prices	$359.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-hnRNP Q antibody (ab103135) at 1/50 dilution + T47D cell lysate at 35 µg

Anti-hnRNP Q antibody - ab136826 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-hnRNP Q antibody (ab136826) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-hnRNP Q antibody - ab172392 from Abcam

Prices	$376.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-hnRNP Q antibody (ab172392) at 1/500 dilutionLane 1 : hnRNP Q transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-hnRNP Q antibody [EPR15096] - C-terminal - ab184946 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR15096

All lanes : Anti-hnRNP Q antibody [EPR15096] - C-terminal (ab184946) at 1/50000 dilutionLane 1 : HepG2 cell lysateLane 2 : HTC116 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.Secondarygoat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilutiondeveloped using the ECL technique

Anti-hnRNP Q antibody [I8E4] - ab10687 from Abcam

Prices	$394.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	I8E4

ab10687 staining hnRNP Q in the HT1080 cell line from Human fibrosarcoma biopsy by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were transfected with scrRNA and then the cells were fixed with ice-cold methanol. Samples were incubated with primary antibody. An Alexa Fluor®488-conjugated Donkey anti-mouse was used as the secondary antibody. DNA staining was performed using DAPI.

Anti-SYNCRIP / HnRNP Q Antibody - LS-C335634 from LifeSpan Bioscience

Prices	$315.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using SYNCRIP antibody.

Anti-SYNCRIP / HnRNP Q Antibody - LS-C346291 from LifeSpan Bioscience

Prices	$255.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunofluorescence blot of MCF7 cell using SYNCRIP antibody. Blue: DAPI for nuclear staining.

Anti-SYNCRIP / HnRNP Q Antibody (aa236-285) IHC-plus™ - LS-B9133 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Human, Brain, neurons: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-SYNCRIP / HnRNP Q Antibody IHC-plus™ - LS-B11374 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11374 concentration 20 ug/ml.

Anti-SYNCRIP / HnRNP Q Antibody (clone I8E4) - LS-C82266 from LifeSpan Bioscience

Prices	$380.00
Sizes	50 µl
Host	Mouse
Clonality	Monoclonal
Clone	I8E4

Anti-SYNCRIP / HnRNP Q Antibody (HRP) - LS-C211698 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (Glu268) - LS-C191924 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (Biotin) - LS-C211701 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (aa401-450) - LS-C31953 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (N-Terminus) - LS-C31342 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (FITC) - LS-C211703 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SYNCRIP / HnRNP Q Antibody (aa219-268) - LS-C292064 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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