Gene Symbol | CTSE |
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Entrez Gene | 1510 |
Alt Symbol | CATE |
Species | Human |
Gene Type | protein-coding |
Description | cathepsin E |
Other Description | erythrocyte membrane aspartic proteinase|slow-moving proteinase |
Swissprots | Q9UCE4 Q9NY58 Q5TZ01 P14091 Q5TZ02 Q9UCE3 |
Accessions | AAA52300 EAW91592 EAW91593 P14091 AJ250716 CAB82849 AJ250717 CAB82850 AK292057 BAF84746 AK298069 BAG60360 AU100136 BC042537 AAH42537 J05036 AAA52130 JF432419 ADZ15636 XM_011509244 XP_011507546 XM_011509245 XP_011507547 NM_001910 NP_001901 NM_148964 NP_683865 |
Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. {ECO:0000269|PubMed:8765029}. |
Subcellular Location | Endosome {ECO:0000269|PubMed:7983070}. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. |
Tissue Specificity | Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B- lymphocytes. {ECO:0000269|PubMed:11322887, ECO:0000269|PubMed:1370478, ECO:0000269|PubMed:8765029}. |
Top Pathways | Lysosome |
Human Cathepsin E full length protein - ab114806 from Abcam
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Human Cathepsin E full length protein - ab151880 from Abcam
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Mouse Cathepsin E full length protein - ab185383 from Abcam
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CTSE / Cathepsin E Antibody Blocking Peptide - LS-E8294 from LifeSpan Bioscience
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CTSE / Cathepsin E Antibody Blocking Peptide - LS-E22015 from LifeSpan Bioscience
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CTSE / Cathepsin E Antibody Blocking Peptide - LS-E22016 from LifeSpan Bioscience
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Cathepsin E Recombinant Protein - H00001510-P01 from Novus Biologicals
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CTSE-Antibody-Center-Blocking-Peptide - BP6568c from Abgent, a WuXi AppTec company
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Recombinant Human Cathepsin E, CF - 1294-AS-010 from R&D Systems
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Human Cathepsin E protein - orb49253 from Biorbyt
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Mouse CTSE His tag protein - orb83959 from Biorbyt
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CTSE Blocking Peptide - 33R-3335 from Fitzgerald
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CTSE protein (His tag) - 80R-3719 from Fitzgerald
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Cathepsin E Blocking Peptide - abx062494 from Abbexa
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Cathepsin E (57-363, His-tag) - AR51406PU-N from Acris Antibodies
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Cathepsin E (57-363, His-tag) - AR51406PU-S from Acris Antibodies
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Cathepsin E - H00001510-P01-10 from Acris Antibodies
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Cathepsin E - H00001510-P01-25 from Acris Antibodies
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Cathepsin E, Human, Recombinant - 19-C400 from ARP American Research Products
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CTSE, 57-363aa Human, His tag, E.coli - 01-P2586 from ARP American Research Products
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Cathepsin E Recombinant Protein - 96-227 from ProSci
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CTSE fusion protein - ag18484 from Proteintech Group
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CTSE fusion protein - Ag18164 from Proteintech Group
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Recombinant Human CTSE Protein - BP001628-C400 from Syd Labs
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Recombinant Human CTSE - CTSE-26489TH from Creative Biomart
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