GAD1

Gene Symbol GAD1
Entrez Gene 2571
Alt Symbol CPSQ1, GAD, SCP
Species Human
Gene Type protein-coding
Description glutamate decarboxylase 1 (brain, 67kDa)
Other Description 67 kDa glutamic acid decarboxylase|GAD-67|glutamate decarboxylase 1|glutamate decarboxylase 67 kDa isoform
Swissprots Q53TQ7 Q49AK1 Q99259 Q9BU91 Q9UHH4
Accessions AAA35900 AAP88035 AAY24237 ABI49508 EAX11228 EAX11229 EAX11230 Q99259 A28074 CAA01913 AF178853 AAF18390 AK127781 AK292582 BAF85271 AK307460 BC002815 AAH02815 BC026349 AAH26349 BC036552 AAH36552 BC037780 AAH37780 DQ892376 ABM83302 DQ895590 ABM86516 L16888 AAB59427 M55574 AAA72938 M70434 AAA52512 M81883 AAA62368 S61897 AAB26937 S61898 AAB26938 Z22750 CAA80435 XM_005246444 XP_005246501 XM_011510922 XP_011509224 NM_000817 NP_000808 NM_013445 NP_038473
Function Catalyzes the production of GABA.
Tissue Specificity Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. {ECO:0000269|PubMed:10671565}.
Top Pathways Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism

GAD1 Antibody - 5305 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from mouse and rat brain using GAD1 Antibody.

GAD-65/67 (C-9) - sc-365180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GAD-65/67 (C-9): sc-365180. Western blot analysis of GAD-67 expression in non-transfected: sc-117752 (A) and human GAD-67 transfected: sc-175894 (B) 293T whole cell lysates.

GAD-67 (A-4) - sc-390383 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GAD-67 (A-4): sc-390383. Western blot analysis of GAD-67 expression in non-transfected: sc-117752 (A) and human GAD-67 transfected: sc-158540 (B) 293T whole cell lysates and mouse brain tissue extract (C).

GAD-65/67 (C-20) - sc-7513 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of GAD-65 expression in rat brain tissue extract immunoprecipitated with GAD-65/67 (C-20): sc-7513 and detected with GAD-65 (GAD-6): sc-32270.

GAD-67 (H-101) - sc-5602 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GAD-67 (H-101): sc-5602. Western blot analysis of GAD-67 expression in U-87 MG whole cell lysate.

GAD-67 (F-6) - sc-28376 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GAD-67 (F-6): sc-28376. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic staining of glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

GAD-67 (N-19) - sc-7512 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GAD-67 (N-19): sc-7512. Western blot analysis of GAD-67 expression in non-transfected: sc-117752 (A) and mouse GAD-67 transfected: sc-126883 (B) 293T whole cell lysates and mouse brain tissue extract (C).

GAD-67 (K-87) - sc-58531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
GAD-67 (K-87): sc-58531. Western blot analysis of GAD-67 expression in non-transfected: sc-117752 (A) and human GAD-67 transfected: sc-158540 (B) 293T whole cell lysates.

Anti-GAD65 + GAD67 antibody - ab49832 from Abcam

Prices $394.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab49832 staining human pancreas tissue sections by IHC-P.  Sections were formaldehyde fixed and subjected to heat mediated antigen retreival in 10mM citrate buffer prior to incubation with ab49832, diluted 1/2000, for 1 hour at 25°C.  An Alexa Fluor® 546 conjugated goat anti-rabbit antibody, diluted 1/200, was used as the secondary.See Abreview

Anti-GAD65 + GAD67 antibody - ab55412 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GAD65 + GAD67 antibody (ab55412) at 1/500 dilutionLane 1 : mouse brain lysate, without immunizing peptideLane 2 : mouse brain lysate, with immunizing peptide

Anti-GAD67 antibody - ab75712 from Abcam

Prices $379.00
Sizes 500 µl
Host Chicken
Clonality Polyclonal

Anti-GAD67 antibody - ab52249 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GAD67 antibody (ab52249) at 1/300 dilutionLane 1 : LOVO cell extract; without peptideLane 2 : LOVO cell extract; with peptide

Anti-GAD67 antibody - ab118906 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) using ab118906 at a concentration of 10 µg/ml.

Anti-GAD67 antibody - ab139393 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GAD67 antibody (ab139393) at 1/500 dilutionLane 1 : extracts from LOVO cell Lane 2 : extracts from LOVO cell treated with the synthesized peptide

Anti-GAD67 antibody - ab99384 from Abcam

Prices $376.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Ab99384 staining GAD67 in human pancreas using immunohistochemistry with formalin fixed, paraffin embedded tissue.

Anti-GAD67 antibody - ab22050 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GAD67 antibody (ab22050) at 0.5 µg/ml + SKNSH cell lysateObserved band size : 67 kDa (why is the actual band size different from the predicted?)

Anti-GAD67 antibody [5D8] - ab117879 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5D8
All lanes : Anti-GAD67 antibody [5D8] (ab117879) at 1/1000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control Lane 2 : HEK293T cells transfected with pCMV6-ENTRY GAD1Lysates/proteins at 5 µg per lane.

Anti-GAD67 antibody [EPR2550] - ab108626 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2550
All lanes : Anti-GAD67 antibody [EPR2550] (ab108626) at 1/1000 dilutionLane 1 : Human fetal brain cell lysateLane 2 : SH-SY5Y cell lysateLane 3 : Human fetal hypothalamus cell lysateLane 4 : Jurkat cell lysateLane 5 : C6 cell lysateLane 6 : Neuro2a cell lysateLysates/proteins at 10 µg per lane.

Anti-GAD67 antibody [K-87] - ab26116 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone K-87
Anti-GAD67 antibody [K-87] (ab26116) at 1/2000 dilution + mouse cerebellum at 0.75 µgSecondaryHRP horse anti-mouse IgG at 1/5000 dilution

Anti-GAD67 antibody, prediluted - ab37403 from Abcam

Prices $376.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal
Ab37403 staining GAD67 in human pancreas using immunohistochemistry with formalin fixed, paraffin embedded tissue.

Anti-GAD67 antibody - C-terminal - ab170312 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GAD67 antibody - C-terminal (ab170312) at 1/100 dilution + HepG2 cell lysate at 35 µg

Anti-GAD / Glutamate Decarboxylase Antibody (C-Terminus) - LS-C57005 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GAD / Glutamate Decarboxylase Antibody - LS-C285794 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GAD / Glutamate Decarboxylase Antibody - LS-C343762 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of GABAergic neurons within lamina I of cat dorsal horn using rabbit polyclonal antiserum to glutamic acid decarboxylase (GAD65/67). Photomicrograph courtesy of Dr TFC Batten, Institute for Cardiovascular Research, University of Leeds, UK.

Anti-GAD / Glutamate Decarboxylase Antibody (aa545-594) IHC-plus™ - LS-B5660 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Glutamate Decarboxylase antibody IHC of human brain cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5660 concentration 10 ug/ml.
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