Gene Symbol | CA9 |
---|---|
Entrez Gene | 768 |
Alt Symbol | CAIX, MN |
Species | Human |
Gene Type | protein-coding |
Description | carbonic anhydrase IX |
Other Description | CA-IX|P54/58N|RCC-associated antigen G250|RCC-associated protein G250|carbonate dehydratase IX|carbonic anhydrase 9|carbonic dehydratase|membrane antigen MN|pMW1|renal cell carcinoma-associated antigen G250 |
Swissprots | Q5T4R1 Q16790 |
Accessions | CBL94025 EAW58359 Q16790 AI023541 AJ010588 CAB82444 AL554705 BC014950 AAH14950 DQ892208 ABM83134 DQ895404 ABM86330 EF122496 ABL67717 X66839 CAA47315 XM_006716869 XP_006716932 XM_006716870 XP_006716933 XR_428428 NM_001216 NP_001207 |
Function | Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. {ECO:0000269|PubMed:18703501}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:8486430}. Nucleus, nucleolus {ECO:0000269|PubMed:8486430}. Cell membrane {ECO:0000269|PubMed:8486430}; Single-pass type I membrane protein {ECO:0000269|PubMed:8486430}. Cell projection, microvillus membrane {ECO:0000269|PubMed:8486430}; Single-pass type I membrane protein {ECO:0000269|PubMed:8486430}. Note=Found on the surface microvilli and in the nucleus, particularly in nucleolus. |
Tissue Specificity | Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. |
Top Pathways | Nitrogen metabolism |
Active human Carbonic Anhydrase IX protein fragment - ab198056 from Abcam
|
||||||||||
Active human Carbonic Anhydrase IX protein fragment - ab174050 from Abcam
|
||||||||||
Human Carbonic Anhydrase IX full length protein - ab114200 from Abcam
|
||||||||||
Human Carbonic Anhydrase IX peptide - ab47011 from Abcam
|
||||||||||
Human Carbonic Anhydrase IX protein fragment - ab186087 from Abcam
|
||||||||||
CA9 / Carbonic Anhydrase IX Antibody Blocking Peptide - LS-E7684 from LifeSpan Bioscience
|
||||||||||
CA9 / Carbonic Anhydrase IX Antibody Blocking Peptide - LS-E7687 from LifeSpan Bioscience
|
||||||||||
CA9 / Carbonic Anhydrase IX Blocking Peptide - LS-E7685 from LifeSpan Bioscience
|
||||||||||
CA9 / Carbonic Anhydrase IX Blocking Peptide - LS-E7686 from LifeSpan Bioscience
|
||||||||||
Carbonic Anhydrase IX/CA9 Peptide - NB100-417PEP from Novus Biologicals
|
||||||||||
Recombinant Human Carbonic Anhydrase IX/CA9 Protein - H00000768-P01 from Novus Biologicals
|
||||||||||
Carbonic Anhydrase IX/CA9 Peptide - P1704 from Novus Biologicals
|
||||||||||
Carbonic Anhydrase IX/CA9 Peptide - P1703 from Novus Biologicals
|
||||||||||
CA9-Antibody-Center-Blocking-Peptide - BP5000e from Abgent, a WuXi AppTec company
|
||||||||||
CA9-Antibody-N-term-Blocking-Peptide - BP5000d from Abgent, a WuXi AppTec company
|
||||||||||
CA9-Antibody-Center-Blocking-Peptide - BP5000b from Abgent, a WuXi AppTec company
|
||||||||||
CA9-Antibody-N-term-Blocking-Peptide - BP5000a from Abgent, a WuXi AppTec company
|
||||||||||
Recombinant Human Carbonic Anhydrase IX, CF - 2188-CA-010 from R&D Systems
|
||||||||||
Recombinant human Carbonic anhydrase 9 (OPCA00603) - OPCA00603 from Aviva Systems Biology
|
||||||||||
Human Carbonic protein - orb245255 from Biorbyt
|
||||||||||
Mouse CA9 His tag protein - orb83960 from Biorbyt
|
||||||||||
Human CA9 Fc tag protein - orb82882 from Biorbyt
|
||||||||||
Canine CA9 protein - orb138291 from Biorbyt
|
||||||||||
Human CA9 His tag protein - orb82883 from Biorbyt
|
||||||||||
Canine CA9 protein (His Tag) - orb138292 from Biorbyt
|