| Gene Symbol |
GPRASP1
|
| Entrez Gene |
9737
|
| Alt Symbol |
GASP, GASP-1, GASP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor associated sorting protein 1
|
| Other Description |
G-protein coupled receptor-associated sorting protein 1
|
| Swissprots |
Q96LA1 O43168 Q5JY77
|
| Accessions |
EAW54730 Q5JY77 AB007903 BAA23715 AW293629 AY044233 AAK95578 BC114552 AAI14553 BP193624 BX489726 BX954816 DA094297 DA104338 DA222893 NM_001099410 NP_001092880 NM_001099411 NP_001092881 NM_001184727 NP_001171656 NM_014710 NP_055525
|
| Function |
Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN1P1/BECN2. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15452121, ECO:0000269|PubMed:23954414}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15452121}.
|
| Tissue Specificity |
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15086532}.
|