Gene Symbol | GPRASP1 |
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Entrez Gene | 9737 |
Alt Symbol | GASP, GASP-1, GASP1 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor associated sorting protein 1 |
Other Description | G-protein coupled receptor-associated sorting protein 1 |
Swissprots | Q96LA1 O43168 Q5JY77 |
Accessions | EAW54730 Q5JY77 AB007903 BAA23715 AW293629 AY044233 AAK95578 BC114552 AAI14553 BP193624 BX489726 BX954816 DA094297 DA104338 DA222893 NM_001099410 NP_001092880 NM_001099411 NP_001092881 NM_001184727 NP_001171656 NM_014710 NP_055525 |
Function | Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN1P1/BECN2. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15452121, ECO:0000269|PubMed:23954414}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15452121}. |
Tissue Specificity | Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15086532}. |
GASP-1 CRISPR/Cas9 KO Plasmid (h) - sc-406921 from Santa Cruz Biotechnology
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GASP-1 HDR Plasmid (h) - sc-406921-HDR from Santa Cruz Biotechnology
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GASP-1 Double Nickase Plasmid (h) - sc-406921-NIC from Santa Cruz Biotechnology
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GASP-1 Double Nickase Plasmid (h2) - sc-406921-NIC-2 from Santa Cruz Biotechnology
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GASP-1 CRISPR Activation Plasmid (h) - sc-406921-ACT from Santa Cruz Biotechnology
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GASP-1 CRISPR Activation Plasmid (h2) - sc-406921-ACT-2 from Santa Cruz Biotechnology
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GASP-1 Lentiviral Activation Particles (h) - sc-406921-LAC from Santa Cruz Biotechnology
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GASP-1 Lentiviral Activation Particles (h2) - sc-406921-LAC-2 from Santa Cruz Biotechnology
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GASP-1 siRNA (h) - sc-90993 from Santa Cruz Biotechnology
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GASP-1 shRNA Plasmid (h) - sc-90993-SH from Santa Cruz Biotechnology
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GASP-1 shRNA (h) Lentiviral Particles - sc-90993-V from Santa Cruz Biotechnology
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GPRASP1 RNAi - H00009737-R02 from Novus Biologicals
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MISSION® esiRNA - EHU101671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9628 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9628 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08144 from Sigma-Aldrich
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GPRASP1 siRNA (Human) - CRH6505 from Cohesion Biosciences
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GPRASP1 - MBS8229519 from MyBioSource
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shRNA set against Human Gprasp1 (NM_014710.4) - SHH307162 from Creative biogene
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shRNA set against Human GPRASP1(NM_014710.4) - SHH101375 from Creative biogene
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shRNA set against Human GPRASP1(NM_001099410.1) - SHH101411 from Creative biogene
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shRNA set against Human GPRASP1(NM_001099411.1) - SHH101459 from Creative biogene
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Human GPRASP1 siRNA - orb267007 from Biorbyt
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GPRASP1 shRNA Plasmid (Human) - CHH6505 from Cohesion Biosciences
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GPRASP1 miRNA 3'UTR clone - MiUTR1H-04228 from Creative biogene
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