| Gene Symbol | GPRASP1 |
|---|---|
| Entrez Gene | 9737 |
| Alt Symbol | GASP, GASP-1, GASP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | G protein-coupled receptor associated sorting protein 1 |
| Other Description | G-protein coupled receptor-associated sorting protein 1 |
| Swissprots | Q96LA1 O43168 Q5JY77 |
| Accessions | EAW54730 Q5JY77 AB007903 BAA23715 AW293629 AY044233 AAK95578 BC114552 AAI14553 BP193624 BX489726 BX954816 DA094297 DA104338 DA222893 NM_001099410 NP_001092880 NM_001099411 NP_001092881 NM_001184727 NP_001171656 NM_014710 NP_055525 |
| Function | Modulates lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN1P1/BECN2. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15452121, ECO:0000269|PubMed:23954414}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15452121}. |
| Tissue Specificity | Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra. {ECO:0000269|PubMed:12142540, ECO:0000269|PubMed:15086532}. |