HSD17B11

Gene Symbol	HSD17B11
Entrez Gene	51170
Alt Symbol	17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (17-beta) dehydrogenase 11
Other Description	17-beta-hydroxysteroid dehydrogenase type XI|CTCL tumor antigen HD-CL-03|CTCL-associated antigen HD-CL-03|cutaneous T-cell lymphoma-associated antigen HD-CL-03|dehydrogenase/reductase SDR family member 8|estradiol 17-beta-dehydrogenase 11|retinal short-chain dehydrogenase/reductase 2|short chain dehydrogenase/reductase family 16C member 2|short chain dehydrogenase/reductase family 16C, member 2
Swissprots	Q9UKU4 Q8NBQ5 Q96HF6
Accessions	AAL48315 EAX05987 Q8NBQ5 AF126780 AAF06939 AF273056 AAM44459 AK075348 BAC11560 AY358553 AAQ88917 BC008650 AAH08650 BC011995 BC014327 AAH14327 BC016367 AAH16367 BC021673 AAH21673 BC036001 AAH36001 BM976691 BU838518 CA775960 CB163647 DA265697 XM_006714232 XP_006714295 XM_011532021 XP_011530323 NM_016245 NP_057329
Function	Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:11165019, ECO:0000269|PubMed:12697717, ECO:0000269|PubMed:9888557}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Hsd17b11 protein fragment - ab101826 from Abcam Category Protein Source E. coli Species Human

HSD17B11 Antibody Blocking Peptide - LS-E14972 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSD17B11 Antibody Blocking Peptide - LS-E14973 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HSD17B11 Antibody Blocking Peptide - LS-E10327 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

hydroxysteroid (17-beta) dehydrogenase 11 Recombinant Protein - H00051170-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human hydroxysteroid (17-beta) dehydrogenase 11 Protein - NBP1-50932 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 100 µg, 500 µg Source E. coli Species Human

HSD17B11-Antibody-N-term-Blocking-Peptide - BP9799a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HSD17B11 Protein (OPPA02607) - OPPA02607 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human HSD17B11 protein - orb168521 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

Human HSD17B11 protein - orb244905 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

HSD17B11 Blocking Peptide - 33R-9080 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HSD17B11 protein (His tag) - 80R-1607 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

17-beta-HSD11 / HSD17B11 (20-285, His-tag) - AR09788PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

17-beta-HSD11 / HSD17B11 (20-285, His-tag) - AR09788PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

17-beta-HSD11 / HSD17B11 - H00051170-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

17-beta-HSD11 / HSD17B11 - H00051170-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

Hydroxysteroid (17-beta) Dehydrogenase 11, Human Recombinant - 228-12201-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

HSD17B11, 20-285aa, Human, His tag, E.coli - 01-1807-11 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Species Human

HSD17B11 fusion protein - Ag11464 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HSD17B11 fusion protein - Ag9596 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

HSD17B11 fusion protein - Ag9278 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HSD17B11 fusion protein - ag11182 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

HSD17B11 Human - ENPS-056 from NeoScientific Category Protein Prices $65.00, $169.00, $4,680.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human HSD17B11 - BP000572-ENZ-049 from Syd Labs Category Protein Prices $160.00, $3,600.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

HSD17B11 Human Protein - GWB-BSP213 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,035.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

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