HSD17B11

Gene Symbol	HSD17B11
Entrez Gene	51170
Alt Symbol	17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2
Species	Human
Gene Type	protein-coding
Description	hydroxysteroid (17-beta) dehydrogenase 11
Other Description	17-beta-hydroxysteroid dehydrogenase type XI|CTCL tumor antigen HD-CL-03|CTCL-associated antigen HD-CL-03|cutaneous T-cell lymphoma-associated antigen HD-CL-03|dehydrogenase/reductase SDR family member 8|estradiol 17-beta-dehydrogenase 11|retinal short-chain dehydrogenase/reductase 2|short chain dehydrogenase/reductase family 16C member 2|short chain dehydrogenase/reductase family 16C, member 2
Swissprots	Q9UKU4 Q8NBQ5 Q96HF6
Accessions	AAL48315 EAX05987 Q8NBQ5 AF126780 AAF06939 AF273056 AAM44459 AK075348 BAC11560 AY358553 AAQ88917 BC008650 AAH08650 BC011995 BC014327 AAH14327 BC016367 AAH16367 BC021673 AAH21673 BC036001 AAH36001 BM976691 BU838518 CA775960 CB163647 DA265697 XM_006714232 XP_006714295 XM_011532021 XP_011530323 NM_016245 NP_057329
Function	Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart. {ECO:0000269|PubMed:10800688, ECO:0000269|PubMed:11165019, ECO:0000269|PubMed:12697717, ECO:0000269|PubMed:9888557}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

17β-HSD11 (S-15) - sc-160113 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Hsd17b11 antibody - ab113490 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Hsd17b11 antibody - ab103087 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Hsd17b11 antibody - ab136109 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Hsd17b11 antibody - ab167686 from Abcam Prices $370.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, AP) - LS-C236401 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, APC) - LS-C236403 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa100-149) - LS-C145865 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa71-120) - LS-C119900 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa35-84) - LS-C116184 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, FITC) - LS-C236405 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, Biotin) - LS-C236404 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, PE) - LS-C236406 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110, Azide-free, HRP) - LS-C249227 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa58-107) - LS-C291880 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa88-118) - LS-C322101 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa81-110) - LS-C165032 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (C-Terminus) - LS-C345807 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 Antibody (aa38-254) - LS-C178506 from LifeSpan Bioscience Prices $255.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

hydroxysteroid (17-beta) dehydrogenase 11 Antibody - NBP1-57081 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

hydroxysteroid (17-beta) dehydrogenase 11 Antibody - NBP1-90334 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

hydroxysteroid (17-beta) dehydrogenase 11 Antibody - H00051170-B01 from Novus Biologicals Prices $359.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-DHRS8 antibody produced in rabbit - SAB4502108 from Sigma-Aldrich Prices $335.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-HSD17B11 antibody produced in rabbit - HPA021608 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

ANTI-HSD17B11(N-TERMINAL) antibody produced in rabbit - SAB1307143 from Sigma-Aldrich Prices $326.00 Sizes 40 tst Host Rabbit Clonality Polyclonal

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