PPP1R12B

Gene Symbol PPP1R12B
Entrez Gene 4660
Alt Symbol MYPT2, PP1bp55
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 12B
Other Description myosin phosphatase target subunit 2|myosin phosphatase, target subunit 2|myosin phosphatase-targeting subunit 2|protein phosphatase 1 regulatory subunit 12B|protein phosphatase 1, regulatory (inhibitor) subunit 12B
Swissprots A8MYF5 Q9HCB7 Q5T506 Q9HCB8 Q2TAI8 Q8N179 O60237 B7ZMN6 Q5VUK2
Accessions AAK00336 EAW91416 EAW91417 EAW91418 EAW91419 EAW91420 EAW91421 EAW91422 EAW91423 EAW91424 EAW91425 O60237 AB003062 BAA28376 AB007972 AB050641 BAB17610 AB050642 BAB17611 AB588820 BAJ22080 AF324888 AAK00337 AK025291 AK098261 AK307591 AL049388 AL050133 AL117460 BC034430 AAH34430 BC071166 AAH71166 BC110907 AAI10908 BC144699 AAI44700 BX501884 DA075060 XM_005245206 XP_005245263 XM_011509573 XP_011507875 XM_011509574 XP_011507876 XM_011509575 XP_011507877 XM_011509576 XP_011507878 XM_011509577 XP_011507879 XM_011509578 XP_011507880 NM_001167857 NP_001161329 NM_001167858 NP_001161330 NM_001197131 NP_001184060 NM_002481 NP_002472 NM_032103 NP_115286 NM_032104 NP_115287 NM_032105
Function Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. {ECO:0000269|PubMed:11067852, ECO:0000269|PubMed:9570949}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments and stress fibers.
Tissue Specificity Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific. {ECO:0000269|PubMed:11067852, ECO:0000269|PubMed:9570949}.
Top Pathways Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, Proteoglycans in cancer, Regulation of actin cytoskeleton

MYPT2 (H-71) - sc-292988 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MYPT2 (H-71): sc-292988. Western blot analysis of MYPT1 expression in non-transfected 293T: sc-117752 (A), human MYPT1 transfected 293T: sc-112086 (B), HeLa (C), HL-60 (D) and Jurkat (E) whole cell lysates.

MYPT2 (N-19) - sc-55860 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Myosin Phosphatase 2 antibody - ab168977 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Myosin Phosphatase 2 antibody (ab168977) at 1 µg/ml + Human kidney lysate at 50 µgSecondaryGoat Anti-Rabbit IgG (H+L)-HRP at 1/7500 dilution

Anti-Myosin Phosphatase 2 antibody - ab168988 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Myosin Phosphatase 2 antibody (ab168988) at 1 µg/mlLane 1 : Myosin Phosphatase 2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Myosin Phosphatase 2 antibody - ab168985 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Myosin Phosphatase 2 antibody (ab168985) at 1 µg/mlLane 1 : Myosin Phosphatase 2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Myosin Phosphatase 2 Antibody - NBP1-87751 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Myosin Phosphatase 2 Antibody [NBP1-87751] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-367

Myosin Phosphatase 2 Antibody - NBP1-87750 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Myosin Phosphatase 2 Antibody [NBP1-87750] Staining of human cell line U-2 OS shows positivity in plasma membrane & cytoskeleton (actin filaments).

Myosin Phosphatase 2 Antibody - H00004660-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Myosin Phosphatase 2 Antibody [H00004660-B01] - analysis of PPP1R12B expression in transfected 293T cell line by PPP1R12B MaxPab polyclonal antibody (B01). Lane 1: PPP1R12B transfected lysate (42.57 KDa). Lane 2: Non-transfected lysate.

Myosin Phosphatase 2 Antibody - H00004660-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Myosin Phosphatase 2 Antibody - H00004660-B02P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Myosin Phosphatase 2 Antibody [H00004660-B02P] - analysis of PPP1R12B expression in transfected 293T cell line by PPP1R12B MaxPab polyclonal antibody. Lane 1: PPP1R12B transfected lysate (42.46 KDa). Lane 2: Non-transfected lysate.

Myosin Phosphatase 2 Antibody - H00004660-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Myosin Phosphatase 2 Antibody [H00004660-B02] - analysis of PPP1R12B expression in transfected 293T cell line by PPP1R12B MaxPab polyclonal antibody (B02). Lane 1: PPP1R12B transfected lysate (43.30 KDa). Lane 2: Non-transfected lysate.

Anti-PPP1R12B antibody produced in rabbit - SAB1410815 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPP1R12B: <B>Cat. No. SAB1410815</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~43.3 kDa using PPP1R12B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PPP1R12B antibody produced in rabbit - HPA024171 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPP1R12B: <B>Cat. No. HPA024171</B>: Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Anti-PPP1R12B antibody produced in mouse - SAB1406159 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPP1R12B: <B>Cat. No. SAB1406159</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.6 kDa using PPP1R12B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PPP1R12B antibody produced in mouse - SAB1409340 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PPP1R12B: <B>Cat. No. SAB1409340</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.5 kDa using PPP1R12B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PPP1R12B antibody produced in rabbit - HPA024640 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPP1R12B: <B>Cat. No. HPA024640</B>: Immunohistochemical staining of human skeletal muscle shows moderate cytoplasmic positivity.

mypt2 antibody - zf125647 from GeneTex

Host Rabbit
Clonality Polyclonal

Myosin Phosphatase 2 antibody - orb221503 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

PPP1R12B antibody - 70R-19469 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

PPP1R12B / MYPT2 antibody - 13366-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Mouse skeletal muscle were subjected to SDS PAGE followed by western blot with 13366-1-AP(PPP1R12B Antibody) at dilution of 1:1600

PPP1R12B / MYPT2 antibody - H00004660-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of PPP1R12B expression in transfected 293T cell line (H00004660-T01) by PPP1R12B MaxPab polyclonal antibody.Lane 1: PPP

PPP1R12B / MYPT2 antibody - H00004660-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of PPP1R12B expression in transfected 293T cell line (H00004660-T01) by PPP1R12B MaxPab polyclonal antibody. Lane 1: PPP1R12B transfected lysate(42.57 KDa). Lane 2: Non-transfected lysate.

PPP1R12B / MYPT2 antibody - H00004660-B02 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of PPP1R12B expression in transfected 293T cell line (H00004660-T02) by PPP1R12B MaxPab polyclonal antibody.Lane 1: PPP

PPP1R12B / MYPT2 antibody - H00004660-B02P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of PPP1R12B expression in transfected 293T cell line (H00004660-T02) by PPP1R12B MaxPab polyclonal antibody. Lane 1: PPP1R12B transfected lysate(42.46 KDa). Lane 2: Non-transfected lysate.

PPP1R12B / MYPT2 antibody - H00004660-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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