PPP1R12B

Gene Symbol PPP1R12B
Entrez Gene 4660
Alt Symbol MYPT2, PP1bp55
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory subunit 12B
Other Description myosin phosphatase target subunit 2|myosin phosphatase, target subunit 2|myosin phosphatase-targeting subunit 2|protein phosphatase 1 regulatory subunit 12B|protein phosphatase 1, regulatory (inhibitor) subunit 12B
Swissprots A8MYF5 Q9HCB7 Q5T506 Q9HCB8 Q2TAI8 Q8N179 O60237 B7ZMN6 Q5VUK2
Accessions AAK00336 EAW91416 EAW91417 EAW91418 EAW91419 EAW91420 EAW91421 EAW91422 EAW91423 EAW91424 EAW91425 O60237 AB003062 BAA28376 AB007972 AB050641 BAB17610 AB050642 BAB17611 AB588820 BAJ22080 AF324888 AAK00337 AK025291 AK098261 AK307591 AL049388 AL050133 AL117460 BC034430 AAH34430 BC071166 AAH71166 BC110907 AAI10908 BC144699 AAI44700 BX501884 DA075060 XM_005245206 XP_005245263 XM_011509573 XP_011507875 XM_011509574 XP_011507876 XM_011509575 XP_011507877 XM_011509576 XP_011507878 XM_011509577 XP_011507879 XM_011509578 XP_011507880 NM_001167857 NP_001161329 NM_001167858 NP_001161330 NM_001197131 NP_001184060 NM_002481 NP_002472 NM_032103 NP_115286 NM_032104 NP_115287 NM_032105
Function Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus. {ECO:0000269|PubMed:11067852, ECO:0000269|PubMed:9570949}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12923170}. Note=Along actomyosin filaments and stress fibers.
Tissue Specificity Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific. {ECO:0000269|PubMed:11067852, ECO:0000269|PubMed:9570949}.
Top Pathways Focal adhesion, Vascular smooth muscle contraction, Oxytocin signaling pathway, Proteoglycans in cancer, Regulation of actin cytoskeleton

MYPT2 CRISPR/Cas9 KO Plasmid (h) - sc-408138 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 HDR Plasmid (h) - sc-408138-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 Double Nickase Plasmid (h) - sc-408138-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 Double Nickase Plasmid (h2) - sc-408138-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 CRISPR Activation Plasmid (h) - sc-408138-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 CRISPR Activation Plasmid (h2) - sc-408138-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 Lentiviral Activation Particles (h) - sc-408138-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 Lentiviral Activation Particles (h2) - sc-408138-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYPT2 siRNA (h) - sc-62653 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYPT2 shRNA Plasmid (h) - sc-62653-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYPT2 shRNA (h) Lentiviral Particles - sc-62653-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU094841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Human Phosphatase - SIHP1029 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0531 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP1030 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0529 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP1028 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0530 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP1031 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17260 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17260 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PPP1R12B siRNA (Human) - CRH3080 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PPP1R12B (NM_002481.3) - SHH381020 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPP1R12B siRNA - orb263582 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPP1R12B shRNA Plasmid (Human) - CHH3080 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
Search more