| Gene Symbol |
VCPIP1
|
| Entrez Gene |
80124
|
| Alt Symbol |
DUBA3, VCIP135
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
valosin containing protein (p97)/p47 complex interacting protein 1
|
| Other Description |
VCP/p47 complex-interacting 135-kDa protein|deubiquitinating protein VCIP135|valosin-containing protein (p97)/p47 complex-interacting protein p135|valosin-containing protein p97/p47 complex-interacting protein 1|valosin-containing protein p97/p47 complex-interacting protein p135
|
| Swissprots |
Q8N3A9 Q86W01 Q96JH7 Q9H5R8 Q504T4 Q86T93
|
| Accessions |
EAW86916 Q96JH7 AB058753 BAB47479 AK026785 BAB15552 AK225580 AK297345 BAG59796 AL832606 CAD89944 AL834476 CAD39135 AM392649 CAL37527 AM393766 CAL38641 BC012498 BC049379 AAH49379 BC062426 BC094799 AAH94799 BC118917 BM980302 CR936659 NM_025054 NP_079330
|
| Function |
Acts as a deubiquitinating enzyme. Necessary for VCP- mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains. {ECO:0000250, ECO:0000269|PubMed:23827681}.
|
| Subcellular Location |
Endoplasmic reticulum {ECO:0000250}. Golgi apparatus, Golgi stack {ECO:0000250}. Note=Associated with Golgi stacks and endoplasmic reticulum. {ECO:0000250}.
|