| Gene Symbol |
F2RL2
|
| Entrez Gene |
2151
|
| Alt Symbol |
PAR-3, PAR3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
coagulation factor II (thrombin) receptor-like 2
|
| Other Description |
Coagulation factor II receptor-like 2 (protease-actovated receptor 3)|protease-activated receptor 3|proteinase-activated receptor 3|proteinase-activated receptor-3|thrombin receptor-like 2
|
| Swissprots |
O00254 B2R754 Q7Z3W3 B4DQ13 Q52M68
|
| Accessions |
AAK51564 EAW95778 O00254 AK298585 BAG60775 AK312848 BAG35701 AL048674 BC093648 AAH93648 BC093650 AAH93650 BC095499 AAH95499 BM989640 BX537386 CAD97628 DC419029 U92971 AAC51218 NM_001256566 NP_001243495 NM_004101 NP_004092
|
| Function |
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. {ECO:0000269|PubMed:10079109}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. {ECO:0000269|PubMed:9614115}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|
![Western Blot: Thrombin Receptor-like 2 Overexpression Lysate (Adult Normal) [NBP2-04264] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Thrombin Receptor-like 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8764_Thrombin%2520Receptor-like%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04264-img0001.jpg)