Gene Symbol | F2RL2 |
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Entrez Gene | 2151 |
Alt Symbol | PAR-3, PAR3 |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor II (thrombin) receptor-like 2 |
Other Description | Coagulation factor II receptor-like 2 (protease-actovated receptor 3)|protease-activated receptor 3|proteinase-activated receptor 3|proteinase-activated receptor-3|thrombin receptor-like 2 |
Swissprots | O00254 B2R754 Q7Z3W3 B4DQ13 Q52M68 |
Accessions | AAK51564 EAW95778 O00254 AK298585 BAG60775 AK312848 BAG35701 AL048674 BC093648 AAH93648 BC093650 AAH93650 BC095499 AAH95499 BM989640 BX537386 CAD97628 DC419029 U92971 AAC51218 NM_001256566 NP_001243495 NM_004101 NP_004092 |
Function | Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. {ECO:0000269|PubMed:10079109}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut. {ECO:0000269|PubMed:9614115}. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human Proteinase Activated Receptor 3 peptide - ab100813 from Abcam
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F2RL2 / PAR3 Antibody Blocking Peptide - LS-E1549 from LifeSpan Bioscience
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F2RL2 / PAR3 Antibody Blocking Peptide - LS-E21988 from LifeSpan Bioscience
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F2RL2 / PAR3 Antibody Blocking Peptide - LS-E28577 from LifeSpan Bioscience
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F2RL2 / PAR3 Blocking Peptide - LS-E28578 from LifeSpan Bioscience
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F2RL2 / PAR3 Antibody Blocking Peptide - LS-E35702 from LifeSpan Bioscience
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F2RL2-Antibody-N-term-Blocking-peptide - BP12288a from Abgent, a WuXi AppTec company
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F2RL2 Blocking Peptide - 33R-7108 from Fitzgerald
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F2RL2 - H00002151-G01 from Acris Antibodies
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PAR3 fusion protein - ag12833 from Proteintech Group
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PAR3 fusion protein - ag12853 from Proteintech Group
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PAR-3 (1-6) (human) - 89789 from NeoScientific
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Recombinant Human PAR3/Thrombin Receptor-like 2 Protein - H00002151-G01 from Novus Biologicals
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PAR-3 (1-6) - abx265070 from Abbexa
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F2RL2 Peptide, Human - M34GP05172H from Creative Peptides
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PAR-3 (1-6) (human) - P4501 from Creative Peptides
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PAR-3 (1-6) (Human) - CCP2734 from Cohesion Biosciences
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Proteinase-activated receptor 3 (F2RL2), Recombinant Protein - MBS7014452 from MyBioSource
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Proteinase-activated receptor 3 (F2RL2), Recombinant Protein - MBS1059302 from MyBioSource
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Human PAR3 (1-6) peptide - orb70945 from Biorbyt
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PAR-3 (1-6) (human) - P4613 from Creative Peptides
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Recombinant Human F2RL2 Protein - F2RL2-3617H from Creative Biomart
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