Gene Symbol | SPHKAP |
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Entrez Gene | 80309 |
Alt Symbol | SKIP |
Species | Human |
Gene Type | protein-coding |
Description | SPHK1 interactor, AKAP domain containing |
Other Description | A-kinase anchor protein SPHKAP|SPHK1 (sphingosine kinase type 1) interacting protein|SPHK1-interactor and AKAP domain-containing protein|sphingosine kinase type 1-interacting protein |
Swissprots | Q2M3C7 Q68DA3 Q9C0I5 Q68DR8 |
Accessions | Q2M3C7 AB051465 BAB21769 AK090876 BAG52242 AK095042 AK125481 AK127071 BC104954 AAI04955 BC104956 AAI04957 BC143408 CR749297 CAH18152 CR749494 CAH18317 HQ258692 ADR83443 XM_005246867 XP_005246924 XM_005246868 XP_005246925 XM_005246870 XP_005246927 XM_006712777 XP_006712840 XM_006712778 XP_006712841 XM_011511925 XP_011510227 XM_011511926 XP_011510228 XM_011511927 XP_011510229 NM_001142644 NP_001136116 NM_030623 NP_085126 |
Function | Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. {ECO:0000269|PubMed:12080051, ECO:0000269|PubMed:20394097}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12080051, ECO:0000269|PubMed:20394097}. Note=Colocalizes with SPHK1 in the cytoplasm. |
Tissue Specificity | Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain. {ECO:0000269|PubMed:12080051, ECO:0000269|PubMed:20394097}. |
SPHKAP (K-16) - sc-244213 from Santa Cruz Biotechnology
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SPHKAP (N-19) - sc-244212 from Santa Cruz Biotechnology
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Anti-SPHKAP antibody - ab155225 from Abcam
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Anti-SPHKAP antibody - ab184779 from Abcam
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Anti-SPHKAP Antibody (C-Terminus) - LS-C347786 from LifeSpan Bioscience
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Anti-SPHKAP Antibody (C-Terminus) IHC-plus⢠- LS-B8794 from LifeSpan Bioscience
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Sphingosine Kinase 1/SPHK1 Antibody - NBP1-22974 from Novus Biologicals
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SPHKAP Antibody - NBP2-30770 from Novus Biologicals
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SPHKAP Antibody - NBP2-30973 from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [DyLight 550] - NBP1-22974R from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [DyLight 488] - NBP1-22974G from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [HRP] - NBP1-22974H from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [Biotin] - NBP1-22974B from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [DyLight 650] - NBP1-22974C from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [DyLight 405] - NBP1-22974V from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [FITC] - NBP1-22974F from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [Alexa Fluor (R) 700] - NBP1-22974AF700 from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [Alexa Fluor (R) 647] - NBP1-22974AF647 from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [Alexa Fluor (R) 488] - NBP1-22974AF488 from Novus Biologicals
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Sphingosine Kinase 1/SPHK1 Antibody [Alexa Fluor (R) 405] - NBP1-22974AF405 from Novus Biologicals
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Anti-SPHKAP antibody produced in rabbit - HPA048168 from Sigma-Aldrich
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Anti-SPHKAP antibody produced in rabbit - HPA042499 from Sigma-Aldrich
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Anti-SPHKAP antibody produced in rabbit - SAB2700014 from Sigma-Aldrich
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SPHKAP antibody - H00080309-B01P from Acris Antibodies
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Rabbit Anti-Human SPHKAP (C-Terminus) - 119-17298 from RayBiotech
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