Gene Symbol | TRIM58 |
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Entrez Gene | 25893 |
Alt Symbol | BIA2 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 58 |
Other Description | E3 ubiquitin-protein ligase TRIM58|tripartite motif-containing 58|tripartite motif-containing protein 58 |
Swissprots | Q8NG06 Q6B0H9 |
Accessions | Q8NG06 AF327057 AAM63958 AK096188 BC074748 AAH74748 BX537432 CAD97674 BX644877 DN998591 NM_015431 NP_056246 |
Function | E3 ubiquitin ligase induced during late erythropoiesis. Directly binds and ubiquitinates the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization. {ECO:0000269|PubMed:25241935}. |
Tissue Specificity | Expressed in erythroblasts. {ECO:0000269|PubMed:25241935}. |
tripartite motif-containing 58, ELISA Kit - MBS9332927 from MyBioSource
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Human TRIM58 ELISA Kit - E039504 from Biobool
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anti-TRIM58 antibody - ARG57182 from Arigo Biolaboratories
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