Gene Symbol | PLVAP |
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Entrez Gene | 83483 |
Alt Symbol | FELS, PV-1, PV1, gp68 |
Species | Human |
Gene Type | protein-coding |
Description | plasmalemma vesicle associated protein |
Other Description | fenestrated endothelial-linked structure protein|fenestrated-endothelial linked structure protein; PV-1 protein|plasmalemma vesicle protein 1|plasmalemma vesicle-associated protein |
Swissprots | Q8ND68 Q86VP0 Q9BX97 Q8N8Y0 Q8TER8 Q9BZD5 |
Accessions | EAW84600 Q9BX97 AF326591 AAK11226 AF348827 AAK20040 AK074054 BAB84880 AK096030 BAC04681 AK313837 AL834363 CAD39027 AW874637 BC050365 AAH50365 BC056414 AAH56414 BX380375 D83199 HQ447733 ADQ32218 NM_031310 NP_112600 |
Function | Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability. {ECO:0000269|PubMed:15155804}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Membrane- associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium. {ECO:0000269|PubMed:11401446, ECO:0000269|PubMed:15971170}. |
PV1 (D-14) - sc-50168 from Santa Cruz Biotechnology
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PV1 (H-66) - sc-367579 from Santa Cruz Biotechnology
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PV1 (PAL-E) - sc-52355 from Santa Cruz Biotechnology
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PV1 (Q-14) - sc-50169 from Santa Cruz Biotechnology
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Anti-PLVAP antibody - ab21848 from Abcam
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Anti-PLVAP antibody - ab103396 from Abcam
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Anti-PLVAP antibody - ab127554 from Abcam
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Anti-PLVAP antibody [174/2] - ab81719 from Abcam
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Anti-PV1 / PLVAP Antibody (clone MECA-32, Biotin) - LS-C58130 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone MECA-32, FITC) - LS-C58132 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone MECA-32, PE) - LS-C74971 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone MECA-32) - LS-C58134 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone MECA-32) - LS-C124385 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody - LS-C124383 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone 174/2) - LS-C140121 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone MECA-32, FITC) - LS-C131447 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone 13A65, FITC) - LS-C183002 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone 1D4B) - LS-C189749 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (clone 174/2, FITC) - LS-C209607 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250, AP) - LS-C223679 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250, APC) - LS-C223680 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250, FITC) - LS-C223683 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250, PE) - LS-C223685 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250, Azide-free, HRP) - LS-C223682 from LifeSpan Bioscience
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Anti-PV1 / PLVAP Antibody (aa221-250) - LS-C324119 from LifeSpan Bioscience
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