LPAR4

Gene Symbol LPAR4
Entrez Gene 2846
Alt Symbol GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9
Species Human
Gene Type protein-coding
Description lysophosphatidic acid receptor 4
Other Description G protein-coupled receptor 23|G-protein coupled receptor 23|LPA receptor 4|LPA-4|P2Y purinoceptor 9|P2Y5-like receptor|purinergic receptor 9
Swissprots Q502U9 Q6NSP5 O15132 B2RAC7 Q99677
Accessions AAB62087 AAB66322 AAC51301 AAP58404 EAW98596 Q99677 AA424772 AK314134 BAG36824 AU129897 BC069996 AAH69996 BC074722 AAH74722 BC095538 AAH95538 BM973092 BX100826 DA368656 DA735126 U90322 AAB62088 XM_005262126 XP_005262183 XM_006724639 XP_006724702 XM_011530921 XP_011529223 NM_001278000 NP_001264929 NM_005296 NP_005287
Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1- alkyl- > 1-alkenyl-LPA. {ECO:0000269|PubMed:12724320}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity High expression in ovary. Not detected in the brain regions thalamus, putamen, caudate, frontal cortex, pons, hypothalamus and hippocampus. {ECO:0000269|PubMed:12724320}.
Top Pathways PI3K-Akt signaling pathway, Rap1 signaling pathway, Neuroactive ligand-receptor interaction

P2Y9 (H-60) - sc-367541 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
P2Y9 (H-60): sc-367541. Western blot analysis of P2Y9 expression in HL-60 (A), KNRK (B), MDA-MB-231 (C), 3T3-L1 (D) and SK-OV-3 (E) whole cell lysates.

P2Y9 (N-20) - sc-46021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
P2Y9 (N-20): sc-46021. Western blot analysis of P2Y9 expression in HL-60 (A) and KNRK (B) whole cell lysates.

P2Y9 (P-18) - sc-46022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

P2Y9 (S-15) - sc-46023 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-P2Y9 antibody - ab115454 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115454, at 20 µg/ml, staining P2Y9 in formalin-fixed, paraffin-embedded Human Brain, Cortex tissue by Immunohistochemistry, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-P2Y9 antibody - ab183076 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-P2Y9 antibody (ab183076) at 1/450 dilutionLane 1 : Human leiomyosarcoma tissue lysateLane 2 : Human liver cancer tissue lysateLysates/proteins at 40 µg per lane.SecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutiondeveloped using the ECL technique

Anti-P2Y9 antibody - ab130325 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-P2Y9 antibody (ab130325) at 1/100 dilution + MDA-MB468 cell lysate at 35 µg

Anti-P2Y9 antibody - N-terminal - ab140822 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labelling P2Y9 with ab140822 at 2 ug/ml.

Anti-LPAR4 / GPR23 Antibody (aa126-156, AP) - LS-C262091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa213-262) - LS-C151794 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LPAR4 / GPR23 antibody Western Blot of 293T.

Anti-LPAR4 / GPR23 Antibody (C-Terminus) - LS-C151795 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
LPAR4 / GPR23 antibody Western Blot of RPMI-8226.

Anti-LPAR4 / GPR23 Antibody (aa126-156, APC) - LS-C262092 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa126-156, Biotin) - LS-C262093 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa126-156, Azide-free, HRP) - LS-C262095 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa126-156, FITC) - LS-C262094 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa126-156) - LS-C322704 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa126-156, PE) - LS-C262096 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LPAR4 / GPR23 Antibody (aa127-156) - LS-C165847 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
LPAR4 Antibody western blot of MDA-MB468 cell line lysates (35 ug/lane). The LPAR4 antibody detected the LPAR4 protein (arrow).

Anti-LPAR4 / GPR23 Antibody (N-Terminus) IHC-plus™ - LS-A1895 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR4 / GPR23 antibody IHC of human brain neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPAR4 / GPR23 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A871 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR4 / GPR23 antibody LS-A871 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPAR4 / GPR23 Antibody (C-Terminus) IHC-plus™ - LS-A872 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR4 / GPR23 antibody LS-A872 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-LPAR4 / GPR23 Antibody (C-Terminus) IHC-plus™ - LS-A873 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-LPAR4 / GPR23 antibody LS-A873 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

P2Y9 Antibody - NBP2-33734 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: P2Y9 Antibody [NBP2-33734] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

P2Y9 Antibody - NBP2-33757 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: P2Y9 Antibody [NBP2-33757] - Staining of human pancreas shows strong cytoplasmic positivity in a subset of islet cells of Langerhans.

P2Y9 Antibody - NLS871 from Novus Biologicals

Prices $369.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: P2Y9 Antibody [NLS871] - Melanoma
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