Gene Symbol | Cebpb |
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Entrez Gene | 24253 |
Alt Symbol | Il6dbp, NF-IL6, TCF5 |
Species | Rat |
Gene Type | protein-coding |
Description | CCAAT/enhancer binding protein (C/EBP), beta |
Other Description | C/EBP beta|CCAAT/enhancer-binding protein beta|IL-6DBP|SF-B|interleukin-6-dependent-binding protein|nuclear factor-IL6|silencer factor B |
Swissprots | P21272 A2VD03 |
Accessions | AAA40972 CAA38443 P21272 BC129071 AAI29072 M57235 AAA19669 S77528 AAB21102 X60769 CAA43179 NM_001301715 NP_001288644 NM_001301720 NP_001288649 NM_024125 NP_077039 |
Function | Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. {ECO:0000269|PubMed:1934061}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Liver and lung. |
Top Pathways | Tuberculosis, TNF signaling pathway, Transcriptional misregulation in cancer |
Recombinant Rat CCAAT/enhancer-binding protein beta(Cebpb) - CSB-YP005181RA CSB-EP005181RA CSB-BP005181RA CSB-MP005181RA from Cusabio
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CCAAT/enhancer-binding protein beta (Cebpb), Recombinant Protein - MBS958714 from MyBioSource
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Recombinant Rat CEBPB Protein - CEBPB-1325R from Creative Biomart
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Rat-Cebpb-S105-Blocking-Peptide - BP20701b from Abgent, a WuXi AppTec company
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