| Gene Symbol | Cebpb |
|---|---|
| Entrez Gene | 24253 |
| Alt Symbol | Il6dbp, NF-IL6, TCF5 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | CCAAT/enhancer binding protein (C/EBP), beta |
| Other Description | C/EBP beta|CCAAT/enhancer-binding protein beta|IL-6DBP|SF-B|interleukin-6-dependent-binding protein|nuclear factor-IL6|silencer factor B |
| Swissprots | P21272 A2VD03 |
| Accessions | AAA40972 CAA38443 P21272 BC129071 AAI29072 M57235 AAA19669 S77528 AAB21102 X60769 CAA43179 NM_001301715 NP_001288644 NM_001301720 NP_001288649 NM_024125 NP_077039 |
| Function | Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Plays an important role in adipose tissue differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG) as well as other adipogenesis key player genes. {ECO:0000269|PubMed:1934061}. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | Liver and lung. |
| Top Pathways | Tuberculosis, TNF signaling pathway, Transcriptional misregulation in cancer |
CompoZr® Knockout ZFN Kit - CKOZFN51896 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND51896 from Sigma-Aldrich
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CEBPB siRNA (Rat) - CRR0060 from Cohesion Biosciences
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CEBPB - MBS8203379 from MyBioSource
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shRNA set against Rat CEBPB (NM_024125.4) - SHH261317 from Creative biogene
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shRNA set against Rat Cebpb(NM_024125.4) - SHG167169 from Creative biogene
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Rat CEBPB siRNA - orb294909 from Biorbyt
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CEBPB shRNA Plasmid (Rat) - CHR0060 from Cohesion Biosciences
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CEBPB miRNA 3'UTR clone - MiUTR1R-00935 from Creative biogene
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