Gene Symbol | KCNK5 |
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Entrez Gene | 8645 |
Alt Symbol | K2p5.1, KCNK5b, TASK-2, TASK2 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, two pore domain subfamily K, member 5 |
Other Description | K2P5.1 potassium channel|TWIK-related acid-sensitive K(+) channel 2|TWIK-related acid-sensitive K+ channel 2|acid-sensitive potassium channel protein TASK-2|potassium channel subfamily K member 5|potassium channel, subfamily K, member 1 (TASK-2)|potassium channel, subfamily, member 5 (KCNK5) |
Swissprots | B5TJL2 Q5VV76 B2RAQ6 O95279 |
Accessions | EAX03979 EAX03980 O95279 AB743589 BAQ22159 AF084830 AAC79458 AK001897 AK314298 BAG36953 BC060793 AAH60793 BC069573 AAH69573 BU608155 EU978936 ACH86095 XM_005249456 XP_005249513 XM_006715235 XP_006715298 NM_003740 NP_003731 |
Function | pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli. |
Top Pathways | Protein digestion and absorption |
TASK-2 (F-7) - sc-271836 from Santa Cruz Biotechnology
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TASK-2 (G-14) - sc-11314 from Santa Cruz Biotechnology
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TASK-2 (H-170) - sc-28632 from Santa Cruz Biotechnology
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TASK-2 (A-18) - sc-11315 from Santa Cruz Biotechnology
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Anti-KCNK5 antibody - ab113966 from Abcam
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Anti-KCNK5 antibody - C-terminal - ab83727 from Abcam
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Anti-KCNK5 / TASK2 Antibody (aa421-470) IHC-plus⢠- LS-B979 from LifeSpan Bioscience
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Anti-KCNK5 / TASK2 Antibody - LS-C309158 from LifeSpan Bioscience
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Anti-KCNK5 / TASK2 Antibody (aa236-285) - LS-C135026 from LifeSpan Bioscience
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Anti-KCNK5 / TASK2 Antibody (aa425-475) - LS-C291082 from LifeSpan Bioscience
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Anti-KCNK5 / TASK2 Antibody (aa459-499) - LS-C291084 from LifeSpan Bioscience
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KCNK5 Antibody - NBP2-32432 from Novus Biologicals
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Anti-KCNK5 antibody produced in rabbit - AV37679 from Sigma-Aldrich
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Monoclonal Anti-KCNK5 antibody produced in mouse - SAB1402995 from Sigma-Aldrich
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Anti-Potassium Channel TASK-2 antibody produced in rabbit - P1106 from Sigma-Aldrich
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Anti-KCNK5 antibody produced in rabbit - HPA059148 from Sigma-Aldrich
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KCNK5 antibody - C-terminal region (ARP37679_P050) - ARP37679_P050 from Aviva Systems Biology
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K2P51-TASK-2-Antibody - AG1132 from Abgent, a WuXi AppTec company
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KCNK5 antibody, C-term - GTX47446 from GeneTex
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KCNK5 antibody - 70R-5224 from Fitzgerald
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KCNK5 antibody - 70R-18084 from Fitzgerald
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Potassium Channel, Subfamily K, Member 5 Antibody - abx114624 from Abbexa
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KCNK5 antibody - 14136-1-AP from Acris Antibodies
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KCNK5 antibody - H00008645-M05 from Acris Antibodies
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KCNK5 Antibody - 28-717 from ProSci
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