| Gene Symbol |
KCNK5
|
| Entrez Gene |
8645
|
| Alt Symbol |
K2p5.1, KCNK5b, TASK-2, TASK2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, two pore domain subfamily K, member 5
|
| Other Description |
K2P5.1 potassium channel|TWIK-related acid-sensitive K(+) channel 2|TWIK-related acid-sensitive K+ channel 2|acid-sensitive potassium channel protein TASK-2|potassium channel subfamily K member 5|potassium channel, subfamily K, member 1 (TASK-2)|potassium channel, subfamily, member 5 (KCNK5)
|
| Swissprots |
B5TJL2 Q5VV76 B2RAQ6 O95279
|
| Accessions |
EAX03979 EAX03980 O95279 AB743589 BAQ22159 AF084830 AAC79458 AK001897 AK314298 BAG36953 BC060793 AAH60793 BC069573 AAH69573 BU608155 EU978936 ACH86095 XM_005249456 XP_005249513 XM_006715235 XP_006715298 NM_003740 NP_003731
|
| Function |
pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
|
| Top Pathways |
Protein digestion and absorption
|
