KCNK5

Gene Symbol KCNK5
Entrez Gene 8645
Alt Symbol K2p5.1, KCNK5b, TASK-2, TASK2
Species Human
Gene Type protein-coding
Description potassium channel, two pore domain subfamily K, member 5
Other Description K2P5.1 potassium channel|TWIK-related acid-sensitive K(+) channel 2|TWIK-related acid-sensitive K+ channel 2|acid-sensitive potassium channel protein TASK-2|potassium channel subfamily K member 5|potassium channel, subfamily K, member 1 (TASK-2)|potassium channel, subfamily, member 5 (KCNK5)
Swissprots B5TJL2 Q5VV76 B2RAQ6 O95279
Accessions EAX03979 EAX03980 O95279 AB743589 BAQ22159 AF084830 AAC79458 AK001897 AK314298 BAG36953 BC060793 AAH60793 BC069573 AAH69573 BU608155 EU978936 ACH86095 XM_005249456 XP_005249513 XM_006715235 XP_006715298 NM_003740 NP_003731
Function pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
Top Pathways Protein digestion and absorption

TASK-2 CRISPR/Cas9 KO Plasmid (h) - sc-408166 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 HDR Plasmid (h) - sc-408166-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 Double Nickase Plasmid (h) - sc-408166-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 Double Nickase Plasmid (h2) - sc-408166-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 CRISPR Activation Plasmid (h) - sc-408166-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 CRISPR Activation Plasmid (h2) - sc-408166-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 Lentiviral Activation Particles (h) - sc-408166-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 Lentiviral Activation Particles (h2) - sc-408166-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TASK-2 siRNA (h) - sc-42341 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TASK-2 shRNA Plasmid (h) - sc-42341-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TASK-2 shRNA (h) Lentiviral Particles - sc-42341-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU076121 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10973 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10973 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10631 from Sigma-Aldrich

Category miRNA

KCNK5 siRNA (Human) - CRH5683 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNK5 RNAi - H00008645-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human KCNK5 (NM_003740.3) - SHH323483 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KCNK5(NM_003740.3) - SHL190200 from Creative biogene

Category siRNA
Species Reactivities Human

Human KCNK5 siRNA - orb266185 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KCNK5 shRNA Plasmid (Human) - CHH5683 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KCNK5 miRNA 3'UTR clone - MiUTR1H-05148 from Creative biogene

Species Reactivities Human
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