PPP2R3C

Gene Symbol PPP2R3C
Entrez Gene 55012
Alt Symbol C14orf10, G4-1, G5pr
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B'', gamma
Other Description protein phosphatase subunit G5PR|rhabdomyosarcoma antigen MU-RMS-40.6A|rhabdomyosarcoma antigen Mu-RMS-40.6C|serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Swissprots D3DS98 Q6P4G2 Q5GJ55 Q9NWR9 Q5GJ56 B4DEN7 Q86TZ3 Q969Q6 D3DS97
Accessions EAW65886 EAW65887 EAW65888 EAW65889 EAW65890 Q969Q6 AA603611 AK000651 BAA91308 AK225447 AK225512 AK293717 BAG57148 AK310700 AK311337 AY157304 AAO17045 AY157305 AAO17046 AY518535 AAT44532 AY518536 AY518537 AAT44533 BC006823 AAH06823 BC010293 AAH10293 BC012563 AAH12563 BC037797 BC063438 AAH63438 BC100021 BI546396 BX248043 CAD62352 DA617813 HQ447258 ADQ31745 XM_005267782 XP_005267839 XM_005267784 XP_005267841 XM_006720184 XP_006720247 XM_011536885 XP_011535187 NM_001305155 NP_001292084 NM_001305156 NP_001292085 NM_017917 NP_060387 NR_130972
Function May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells. {ECO:0000250|UniProtKB:Q9JK24, ECO:0000269|PubMed:24333728}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15820313}. Cytoplasm {ECO:0000269|PubMed:15820313}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. {ECO:0000269|PubMed:15820313}.
Tissue Specificity Ubiquitously expressed in brain and other tissues. {ECO:0000269|PubMed:12167160, ECO:0000269|PubMed:15820313}.
Top Pathways mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway

PPP2R3C (T-12) - sc-137684 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PPP2R3C antibody - ab102942 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PPP2R3C antibody (ab102942) at 1/100 dilution + Y97 cell lysate at 35 µg

Anti-PPP2R3C antibody - ab137946 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PPP2R3C antibody (ab137946) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-PPP2R3C Antibody (aa57-87, AP) - LS-C238602 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa57-87, APC) - LS-C238603 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa146-195) - LS-C200517 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using PPP2R3C antibody.

Anti-PPP2R3C Antibody (aa57-87, Biotin) - LS-C238604 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa57-87, FITC) - LS-C238605 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa57-87, PE) - LS-C238606 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa57-87, Azide-free, HRP) - LS-C248386 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa165-214) - LS-C291385 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa57-87) - LS-C329937 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PPP2R3C Antibody (aa58-107) - LS-C146287 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPP2R3C antibody LS-C146287 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-PPP2R3C Antibody (aa50-79) - LS-C163312 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
P2R3C Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

G5pr Antibody - NBP1-89907 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: G5pr Antibody [NBP1-89907] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

G5pr Antibody - H00055012-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: G5pr Antibody [H00055012-B01] - analysis of C14orf10 expression in transfected 293T cell line by C14orf10 MaxPab polyclonal antibody (B01). Lane 1: C14orf10 transfected lysate (53.30 KDa). Lane 2: Non-transfected lysate.

G5pr Antibody - H00055012-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: G5pr Antibody [H00055012-B01P] - Analysis of PPP2R3C expression in transfected 293T cell line by PPP2R3C polyclonal antibody. Lane 1: C14orf10 transfected lysate(49.83 KDa). Lane 2: Non-transfected lysate.

ANTI-P2R3C(N-TERMINAL) antibody produced in rabbit - SAB1306447 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-P2R3C (N-term): <B>Cat. No. SAB1306447</B>: Western blot analysis of P2R3C Antibody (N-term) in Y79 cell line lysates (35 μg/lane).

Anti-PPP2R3C antibody produced in mouse - SAB1400980 from Sigma-Aldrich

Prices $347.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PPP2R3C, antibody produced in mouse, unpurified immunoglobulin: <B>Cat. No. SAB1400980</B>: Antibody concentration: 1/1000x dilution. Specific band of ~49.83 kDa using PPP2R3C transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-G4-1 antibody produced in chicken - GW21284 from Sigma-Aldrich

Host Chicken
Clonality Polyclonal

Anti-PPP2R3C antibody produced in rabbit - HPA040835 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PPP2R3C: <B>Cat. No. HPA040835</B>: Immunohistochemical staining of human liver shows strong granular cytoplasmic positivity in hepatocytes.

P2R3C-Antibody-N-term - AP9743a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of P2R3C Antibody (N-term) (Cat. #AP9743a) in Y79 cell line lysates (35ug/lane). P2R3C (arrow) was detected using the purified Pab.

PPP2R3C Antibody - N-terminal region (OAAB06343) - OAAB06343 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PPP2R3C Antibody (OAAF04266) - OAAF04266 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PPP2R3C Antibody (OAAF06963) - OAAF06963 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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