PPP2R3C

Gene Symbol PPP2R3C
Entrez Gene 55012
Alt Symbol C14orf10, G4-1, G5pr
Species Human
Gene Type protein-coding
Description protein phosphatase 2, regulatory subunit B'', gamma
Other Description protein phosphatase subunit G5PR|rhabdomyosarcoma antigen MU-RMS-40.6A|rhabdomyosarcoma antigen Mu-RMS-40.6C|serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma
Swissprots D3DS98 Q6P4G2 Q5GJ55 Q9NWR9 Q5GJ56 B4DEN7 Q86TZ3 Q969Q6 D3DS97
Accessions EAW65886 EAW65887 EAW65888 EAW65889 EAW65890 Q969Q6 AA603611 AK000651 BAA91308 AK225447 AK225512 AK293717 BAG57148 AK310700 AK311337 AY157304 AAO17045 AY157305 AAO17046 AY518535 AAT44532 AY518536 AY518537 AAT44533 BC006823 AAH06823 BC010293 AAH10293 BC012563 AAH12563 BC037797 BC063438 AAH63438 BC100021 BI546396 BX248043 CAD62352 DA617813 HQ447258 ADQ31745 XM_005267782 XP_005267839 XM_005267784 XP_005267841 XM_006720184 XP_006720247 XM_011536885 XP_011535187 NM_001305155 NP_001292084 NM_001305156 NP_001292085 NM_017917 NP_060387 NR_130972
Function May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells. {ECO:0000250|UniProtKB:Q9JK24, ECO:0000269|PubMed:24333728}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15820313}. Cytoplasm {ECO:0000269|PubMed:15820313}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. {ECO:0000269|PubMed:15820313}.
Tissue Specificity Ubiquitously expressed in brain and other tissues. {ECO:0000269|PubMed:12167160, ECO:0000269|PubMed:15820313}.
Top Pathways mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway

Human PPP2R3C full length protein - ab162929 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162929 on a 12.5% SDS-PAGE stained with Coomassie Blue.

PPP2R3C Antibody Blocking Peptide - LS-E20806 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PPP2R3C Antibody Blocking Peptide - LS-E10292 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human G5pr Protein - H00055012-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

P2R3C-Antibody-N-term-Blocking-Peptide - BP9743a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PPP2R3C - H00055012-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

PPP2R3C - H00055012-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

PPP2R3C fusion protein - ag18987 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

PPP2R3C fusion protein - Ag19282 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PPP2R3C - TP301497 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PPP2R3C

G5pr Recombinant Protein Antigen - NBP1-89907PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PPP2R3C Peptide, Human - M34GP12278H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

G5pr Recombinant Protein Antigen - NBP2-58168PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (PPP2R3C), Recombinant Protein - MBS1416062 from MyBioSource

Category Protein
Prices $1,235.00, $1,235.00, $1,455.00, $1,455.00, $2,005.00, $2,005.00, $2,470.00, $2,470.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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