MCOLN1

Gene Symbol MCOLN1
Entrez Gene 57192
Alt Symbol MG-2, ML4, MLIV, MST080, MSTP080, TRP-ML1, TRPM-L1, TRPML1
Species Human
Gene Type protein-coding
Description mucolipin 1
Other Description mucolipidin|mucolipidosis type IV protein|mucolipin-1
Swissprots Q7Z4F7 D6W647 Q9H4B3 Q9H292 Q9GZU1 Q9H4B5
Accessions AAG00798 AAG42242 EAW69031 EAW69032 EAW69033 EAW69034 Q9GZU1 AA831948 AF171088 AAQ13604 AF249319 AAG10422 AF287269 AAG00797 AJ293659 CAC07813 AJ293970 CAC08215 AK026102 BAB15360 AK222673 BAD96393 AK294330 BAG57602 AK310109 BC005149 AAH05149 DC356874 DQ891844 ABM82770 DQ895032 ABM85958 NM_020533 NP_065394
Function Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis. {ECO:0000269|PubMed:12459486, ECO:0000269|PubMed:14749347}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed in adult and fetal tissues. {ECO:0000269|PubMed:10973263, ECO:0000269|PubMed:11013137, ECO:0000269|PubMed:11030752}.
Top Pathways Lysosome

Human Mucolipin 1 full length protein - ab153445 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153445 on a 12.5% SDS-PAGE stained with Coomassie Blue.

MCOLN1 / Mucolipin 1 Antibody Blocking Peptide - LS-E2516 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

MCOLN1 / Mucolipin 1 Antibody Blocking Peptide - LS-E12553 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Mucolipin 1 Blocking Peptide - NB110-82375PEP from Novus Biologicals

Category Peptide
Prices $69.00
Sizes 100 µl

Recombinant Human Mucolipin 1 Protein - H00057192-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

MCOLN1-Antibody-C-term-Blocking-peptide - BP13551b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Mucolipin 1 Blocking Peptide - 33R-3049 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Mucolipin-1 - H00057192-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Mucolipin-1 - H00057192-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

MCOLN1 fusion protein - Ag7493 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human MCOLN1, His-tagged - MCOLN1-784H from Creative Biomart

Category Protein
Source E.coli
Species Human

Mucolipin 1 Recombinant Protein Antigen - NBP1-92152PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

MCOLN1 Peptide, Human - M34GP09324H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Mucolipin-1 (MCOLN1), Recombinant Protein - MBS7020011 from MyBioSource

Category Protein
Prices $1,375.00, $2,360.00, $3,565.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Human
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