MCOLN1

Gene Symbol MCOLN1
Entrez Gene 57192
Alt Symbol MG-2, ML4, MLIV, MST080, MSTP080, TRP-ML1, TRPM-L1, TRPML1
Species Human
Gene Type protein-coding
Description mucolipin 1
Other Description mucolipidin|mucolipidosis type IV protein|mucolipin-1
Swissprots Q7Z4F7 D6W647 Q9H4B3 Q9H292 Q9GZU1 Q9H4B5
Accessions AAG00798 AAG42242 EAW69031 EAW69032 EAW69033 EAW69034 Q9GZU1 AA831948 AF171088 AAQ13604 AF249319 AAG10422 AF287269 AAG00797 AJ293659 CAC07813 AJ293970 CAC08215 AK026102 BAB15360 AK222673 BAD96393 AK294330 BAG57602 AK310109 BC005149 AAH05149 DC356874 DQ891844 ABM82770 DQ895032 ABM85958 NM_020533 NP_065394
Function Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis. {ECO:0000269|PubMed:12459486, ECO:0000269|PubMed:14749347}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed in adult and fetal tissues. {ECO:0000269|PubMed:10973263, ECO:0000269|PubMed:11013137, ECO:0000269|PubMed:11030752}.
Top Pathways Lysosome

mucolipin 1 CRISPR/Cas9 KO Plasmid (h) - sc-403931 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 HDR Plasmid (h) - sc-403931-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 Double Nickase Plasmid (h) - sc-403931-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 Double Nickase Plasmid (h2) - sc-403931-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 CRISPR Activation Plasmid (h) - sc-403931-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 CRISPR Activation Plasmid (h2) - sc-403931-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 Lentiviral Activation Particles (h) - sc-403931-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 Lentiviral Activation Particles (h2) - sc-403931-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mucolipin 1 siRNA (h) - sc-44519 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mucolipin 1 shRNA Plasmid (h) - sc-44519-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mucolipin 1 shRNA (h) Lentiviral Particles - sc-44519-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU062561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2460 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2460 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00750 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00750

MCOLN1 siRNA (Human) - CRJ1391 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Mucolipin 1 RNAi - H00057192-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MCOLN1 (NM_020533.2) - SHH339399 from Creative biogene

Category siRNA
Species Reactivities Human

MCOLN1 shRNA Plasmid (Human) - CHJ1391 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCOLN1 miRNA 3'UTR clone - MiUTR3H-07512 from Creative biogene

Species Reactivities Human
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