GNAS

Gene Symbol GNAS
Entrez Gene 2778
Alt Symbol AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH, SgVI
Species Human
Gene Type protein-coding
Description GNAS complex locus
Other Description adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas|neuroendocrine secretory protein|protein ALEX|secretogranin VI
Swissprots Q5JW67 P04895 P84996 Q6NXS0 O75684 Q96H70 Q9NY42 Q32P26 E1P5G5 Q5JWD5 O95467 E1P5G3 E1P5G2 Q14433 O75685 O95417 Q5JWD4 P63092 A6NI00 Q6NR75 Q5JWD2 Q5JWF1 A2A2S3 B2RB88 A2A2S4 Q8TBC0 Q5JWF2 Q12927
Accessions AAA53146 AAA53147 AAA53148 AAA53149 AAB60334 AAD11804 AAX51890 CAA08889 CAA12165 CAB83214 CAB83215 EAW75457 EAW75458 EAW75459 EAW75460 EAW75461 EAW75462 EAW75463 EAW75464 EAW75465 EAW75466 EAW75467 EAW75468 EAW75469 EAW75470 EAW75471 O95467 P63092 P84996 Q5JWF2 AF064092 AAC16860 AF088184 AAC34896 AF088185 AAC34897 AF105253 AAF63226 AF493897 AAM12611 AF493898 AAM12612 AJ224867 CAA12164 AK026564 AK054862 AK093534 AK122771 AK225818 AK314549 BAG37135 AK315860 BAF98751 AK315874 BAF98765 BC002722 AAH02722 BC008855 AAH08855 BC022875 AAH22875 BC036081 BC066923 AAH66923 BC089157 AAH89157 BC104928 AAI04929 BC108315 AAI08316 BT009905 AAP88907 CA335150 CX869731 DB037677 EU832170 ACE87520 EU832264 ACE86834 HQ448266 ADQ32746 M14631 AAA52583 M77026 X04408 CAA27996 X04409 CAA27997 X07036 CAA30084 X56009 CAA39484 NM_000516 NP_000507 NM_001077488 NP_001070956 NM_001077489 NP_001070957 NM_001077490 NP_001070958 NM_016592 NP_057676 NM_080425 NP_536350 NM_080426 NP_536351 NR_003259
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2. {ECO:0000269|PubMed:12391161}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Neuroendocrine secretory granules. {ECO:0000250}.
Top Pathways Oxytocin signaling pathway, Thyroid hormone synthesis, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Vibrio cholerae infection

NESP55 (FL-245) - sc-98548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NESP55 (FL-245): sc-98548. Western blot analysis of NESP55 expression in Ramos whole cell lysate.

G α s (A-16) - sc-26766 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G<sub>α s</sub> (A-16): sc-26766. Western blot analysis of G<sub>α s</sub> expression in TT whole cell lysate.

G α s (C-17) - sc-46975 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G<sub>α s</sub> (C-17): sc-46975. Western blot analysis of G<sub>α s</sub> expression in 293T whole cell lysate.

G α s (C-19) - sc-46976 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G<sub>α s </sub>(C-19): sc-46976. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.

G α s (K-20) - sc-823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G<sub>α s</sub> (K-20): sc-823. Western blot analysis of rat recombinant G<sub>β s</sub> fusion protein.

G α s (12) - sc-135914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G<sub>α s</sub> (12): sc-135914. Western blot analysis of G<sub>α s</sub> expression in Jurkat whole cell lysate.

XLαs (M-14) - sc-18993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XLαs (M-14): sc-18993. Western blot analysis of XLαs expression in A549 (A), Jurkat (B), HEK293 (C), NCI-H460 (D) and MCF7 (E) whole cell lysates.

XLαs (D-20) - sc-18989 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

XLαs (N-19) - sc-18987 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-G protein alpha antibody - ab150823 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human colon tissue, labelling G protein alpha with ab150823 at 1/20 dilution.

Anti-G protein alpha antibody - ab135788 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-G protein alpha antibody (ab135788) at 1/100 dilution + Ramos cell line lysate at 35 µg

Anti-G protein alpha S antibody - ab203194 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded rat brain tissue, labeling G protein alpha S using ab203194 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-G protein alpha S antibody [1H10E5C3] - ab170056 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H10E5C3
Anti-G protein alpha S antibody [1H10E5C3] (ab170056) at 1/1000 dilution + MEF whole cell lysate

Anti-NESP55 antibody - ab150798 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli. Recommended concentration of ab150798 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-GNAS Antibody (aa1028-1037) - LS-C24097 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAS Antibody (aa297-346) - LS-C31963 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-GNAS Antibody (aa121-170) - LS-C80456 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-GNAS Antibody (aa51-100) - LS-C31914 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
GNAS antibody LS-C31914 was used in IHC to stain formalin-fixed, paraffin-embedded human lung.

Anti-GNAS Antibody (aa287-315) - LS-C159745 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
GNAS Antibody(Ascites)western blot of mouse brain tissue lysates (35 ug/lane). The GNAS antibody detected the GNAS protein (arrow).

Anti-GNAS Antibody (aa216-244, AP) - LS-C235775 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAS Antibody (aa721-734) - LS-C113002 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
GNAS antibody (1 ug/ml) staining of Jurkat lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-GNAS Antibody (aa216-244, APC) - LS-C235776 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAS Antibody (aa216-244, Biotin) - LS-C235777 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAS Antibody (aa216-244, PE) - LS-C235779 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GNAS Antibody (aa216-244, FITC) - LS-C235778 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more