GNAS

Gene Symbol	GNAS
Entrez Gene	2778
Alt Symbol	AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH, SgVI
Species	Human
Gene Type	protein-coding
Description	GNAS complex locus
Other Description	adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas|neuroendocrine secretory protein|protein ALEX|secretogranin VI
Swissprots	Q5JW67 P04895 P84996 Q6NXS0 O75684 Q96H70 Q9NY42 Q32P26 E1P5G5 Q5JWD5 O95467 E1P5G3 E1P5G2 Q14433 O75685 O95417 Q5JWD4 P63092 A6NI00 Q6NR75 Q5JWD2 Q5JWF1 A2A2S3 B2RB88 A2A2S4 Q8TBC0 Q5JWF2 Q12927
Accessions	AAA53146 AAA53147 AAA53148 AAA53149 AAB60334 AAD11804 AAX51890 CAA08889 CAA12165 CAB83214 CAB83215 EAW75457 EAW75458 EAW75459 EAW75460 EAW75461 EAW75462 EAW75463 EAW75464 EAW75465 EAW75466 EAW75467 EAW75468 EAW75469 EAW75470 EAW75471 O95467 P63092 P84996 Q5JWF2 AF064092 AAC16860 AF088184 AAC34896 AF088185 AAC34897 AF105253 AAF63226 AF493897 AAM12611 AF493898 AAM12612 AJ224867 CAA12164 AK026564 AK054862 AK093534 AK122771 AK225818 AK314549 BAG37135 AK315860 BAF98751 AK315874 BAF98765 BC002722 AAH02722 BC008855 AAH08855 BC022875 AAH22875 BC036081 BC066923 AAH66923 BC089157 AAH89157 BC104928 AAI04929 BC108315 AAI08316 BT009905 AAP88907 CA335150 CX869731 DB037677 EU832170 ACE87520 EU832264 ACE86834 HQ448266 ADQ32746 M14631 AAA52583 M77026 X04408 CAA27996 X04409 CAA27997 X07036 CAA30084 X56009 CAA39484 NM_000516 NP_000507 NM_001077488 NP_001070956 NM_001077489 NP_001070957 NM_001077490 NP_001070958 NM_016592 NP_057676 NM_080425 NP_536350 NM_080426 NP_536351 NR_003259
Function	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2. {ECO:0000269|PubMed:12391161}.
Subcellular Location	Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Neuroendocrine secretory granules. {ECO:0000250}.
Top Pathways	Oxytocin signaling pathway, Thyroid hormone synthesis, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Vibrio cholerae infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human G protein alpha S full length protein - ab158540 from Abcam Category Protein Source Wheat germ Species Human

Human Histamine H2 Receptor + GsaL fusion full length protein - ab90398 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Histamine H2 Receptor + G saS fusion full length protein - ab90399 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human Histamine H2 Receptor co-expressed with G saS full length protein - ab90408 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

GNAS Antibody Blocking Peptide - LS-E5985 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAS Antibody Blocking Peptide - LS-E27377 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAS Antibody Blocking Peptide - LS-E15725 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GNAS Antibody Blocking Peptide - LS-E8512 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human G protein alpha Protein - H00002778-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

GNAS-Antibody-C-term-Blocking-peptide - BP13065b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GNAS-Antibody-C-term-Blocking-Peptide - BP18552b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GNAS-Antibody-Center-Blocking-Peptide - BP6865c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GNAS blocking peptide - GTX88107-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

Goat anti GNAS antibody Immunizing peptide - orb17558 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

GNAS Blocking Peptide - 33R-8471 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNAS Blocking Peptide - 33R-10097 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNAS Blocking Peptide - 33R-6814 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GNAS Blocking Peptide - 33R-9925 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

G Protein alpha S Peptide - AC21-2202-P from Abcore Category Protein Prices $160.00 Sizes 100 µg

Protein ALEX - H00002778-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Protein ALEX - H00002778-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GNAS Peptide - 42-594P from ProSci Category Peptide Species Human, Mouse, Rat

NESP55,GNAS fusion protein - Ag0197 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human GNAS, GST-tagged - GNAS-1264H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas(GNAS) ,partial - CSB-YP692287HU CSB-EP692287HU CSB-BP692287HU CSB-MP692287HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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