GNAS

Gene Symbol GNAS
Entrez Gene 2778
Alt Symbol AHO, C20orf45, GNAS1, GPSA, GSA, GSP, NESP, PHP1A, PHP1B, PHP1C, POH, SgVI
Species Human
Gene Type protein-coding
Description GNAS complex locus
Other Description adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas|neuroendocrine secretory protein|protein ALEX|secretogranin VI
Swissprots Q5JW67 P04895 P84996 Q6NXS0 O75684 Q96H70 Q9NY42 Q32P26 E1P5G5 Q5JWD5 O95467 E1P5G3 E1P5G2 Q14433 O75685 O95417 Q5JWD4 P63092 A6NI00 Q6NR75 Q5JWD2 Q5JWF1 A2A2S3 B2RB88 A2A2S4 Q8TBC0 Q5JWF2 Q12927
Accessions AAA53146 AAA53147 AAA53148 AAA53149 AAB60334 AAD11804 AAX51890 CAA08889 CAA12165 CAB83214 CAB83215 EAW75457 EAW75458 EAW75459 EAW75460 EAW75461 EAW75462 EAW75463 EAW75464 EAW75465 EAW75466 EAW75467 EAW75468 EAW75469 EAW75470 EAW75471 O95467 P63092 P84996 Q5JWF2 AF064092 AAC16860 AF088184 AAC34896 AF088185 AAC34897 AF105253 AAF63226 AF493897 AAM12611 AF493898 AAM12612 AJ224867 CAA12164 AK026564 AK054862 AK093534 AK122771 AK225818 AK314549 BAG37135 AK315860 BAF98751 AK315874 BAF98765 BC002722 AAH02722 BC008855 AAH08855 BC022875 AAH22875 BC036081 BC066923 AAH66923 BC089157 AAH89157 BC104928 AAI04929 BC108315 AAI08316 BT009905 AAP88907 CA335150 CX869731 DB037677 EU832170 ACE87520 EU832264 ACE86834 HQ448266 ADQ32746 M14631 AAA52583 M77026 X04408 CAA27996 X04409 CAA27997 X07036 CAA30084 X56009 CAA39484 NM_000516 NP_000507 NM_001077488 NP_001070956 NM_001077489 NP_001070957 NM_001077490 NP_001070958 NM_016592 NP_057676 NM_080425 NP_536350 NM_080426 NP_536351 NR_003259
Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2. {ECO:0000269|PubMed:12391161}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Secreted {ECO:0000250}. Note=Neuroendocrine secretory granules. {ECO:0000250}.
Top Pathways Oxytocin signaling pathway, Thyroid hormone synthesis, Inflammatory mediator regulation of TRP channels, Calcium signaling pathway, Vibrio cholerae infection

G α s CRISPR/Cas9 KO Plasmid (h) - sc-400476 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s HDR Plasmid (h) - sc-400476-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s Double Nickase Plasmid (h) - sc-400476-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s Double Nickase Plasmid (h2) - sc-400476-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s CRISPR Activation Plasmid (h) - sc-400476-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s CRISPR Activation Plasmid (h2) - sc-400476-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s Lentiviral Activation Particles (h) - sc-400476-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s Lentiviral Activation Particles (h2) - sc-400476-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G α s siRNA (h) - sc-29328 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G α s shRNA Plasmid (h) - sc-29328-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G α s shRNA (h) Lentiviral Particles - sc-29328-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G protein alpha RNAi - H00002778-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

G protein alpha RNAi - H00002778-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU117321 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1354 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1354 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03985 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03985

GNAS siRNA (Human) - CRH1847 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAS siRNA (Human) - CRH1848 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAS siRNA (Human) - CRH1849 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAS siRNA (Human) - CRH1850 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

G protein alpha RNAi - H00002778-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

G protein alpha RNAi - H00002778-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GNAS - MBS8220190 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GNAS - MBS8240226 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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