FBXO7

Gene Symbol	FBXO7
Entrez Gene	25793
Alt Symbol	FBX, FBX07, FBX7, PARK15, PKPS
Species	Human
Gene Type	protein-coding
Description	F-box protein 7
Other Description	F-box only protein 7
Swissprots	Q9UF21 B4DWX5 Q9UKT2 Q96HM6 Q5TGC4 B4DNB3 Q9Y3I1 Q5TI86
Accessions	EAW60023 EAW60024 EAW60025 EAW60026 Q9Y3I1 AF129537 AAF04471 AF233225 AAF67155 AK054739 AK226087 AK291972 BAF84661 AK297841 BAG60175 AK301716 BAG63187 AL050254 CAB43356 AM392740 CAL37618 BC008361 AAH08361 BC041004 BI821903 BQ326686 BU584368 BX362053 BX409547 BX648151 BX648220 BX648644 CAI46263 CR456491 CAG30377 CU013088 CAK54519 CU013376 CAK54818 EU176789 ABW03590 EU176790 ABW03591 XM_011530106 XP_011528408 NM_001033024 NP_001028196 NM_001257990 NP_001244919 NM_012179 NP_036311
Function	Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination. {ECO:0000269|PubMed:15145941, ECO:0000269|PubMed:16510124, ECO:0000269|PubMed:23933751}.
Subcellular Location	Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Note=Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FBXO7 full length protein - ab161784 from Abcam Category Protein Source Wheat germ Species Human

Human FBXO7 protein fragment - ab161785 from Abcam Category Protein Source Wheat germ Species Human

FBXO7 Antibody Blocking Peptide - LS-E15880 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FBXO7 Protein - H00025793-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FBXO7 Recombinant Protein - H00025793-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

FBXO7 Blocking Peptide - 33R-7101 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXO7 - H00025793-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

FBXO7 - H00025793-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

FBXO7 - H00025793-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

FBXO7 - H00025793-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FBXO7 - H00025793-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FBXO7 fusion protein - ag1035 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

FBXO7 Protein - abx164370 from Abbexa Category Protein Species Human, Mouse, Rat

FBXO7 Recombinant Protein Antigen - NBP1-84713PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FBXO7 Peptide, Human - M34GP05618H from Creative Peptides Category Peptide Source Synthetic. Species Human

FBXO7 Blocking Peptide - CBP7495 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

FBXO7 Recombinant Protein Antigen - NBP2-58563PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

FBXO7 peptide - orb382400 from Biorbyt Category Peptide Species Human, Mouse

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