BTF3

Gene Symbol BTF3
Entrez Gene 689
Alt Symbol BETA-NAC, BTF3a, BTF3b, NACB
Species Human
Gene Type protein-coding
Description basic transcription factor 3
Other Description NAC-beta|RNA polymerase B transcription factor 3|nascent polypeptide-associated complex subunit beta|nascent-polypeptide-associated complex beta polypeptide|transcription factor BTF3
Swissprots A8K510 Q76M56 Q13893 P20290
Accessions AAA58398 EAW95723 EAW95724 EAW95725 EAW95726 EAW95727 EAW95728 P20290 AB062126 BAB93458 AK225964 AK291125 BAF83814 AK310919 BC008062 AAH08062 BC061913 BG182166 BT007120 AAP35784 BU661989 BX359147 DQ892976 ABM83902 DQ896224 ABM87223 X53280 CAA37375 X74070 CAA52200 NM_001037637 NP_001032726 NM_001207 NP_001198
Function When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. {ECO:0000269|PubMed:10982809}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10982809}. Nucleus {ECO:0000269|PubMed:10982809}. Note=The heterodimer with NACA is cytoplasmic.

BTF3a (A-15) - sc-10057 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BTF3a (A-15): sc-10057. Western blot analysis of BTF3a expression in HeLa (A), MCF7 (B) and HL-60 (C) nuclear extracts and MDA-MB-468 (D) whole cell lysate.

BTF3a/b (C-7) - sc-166141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BTF3a/b (C-7): sc-166141. Western blot analysis of BTF3a/b expression in HeLa (A) and MCF7 (B) nuclear extracts.

BTF3a/b (C-19) - sc-10059 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BTF3a/b (C-19): sc-10059. Western blot analysis of BTF3L4 expression in non-transfected: sc-117752 (A) and mouse BTF3L4 transfected: sc-125065 (B) 293T whole cell lysates.

BTF3a/b (FL-206) - sc-28717 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BTF3a/b (FL-206): sc-28717. Western blot analysis of BTF3a/b expression in HeLa whole cell lysate.

BTF3a/b (H-9) - sc-166094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BTF3a/b (H-9): sc-166094. Western blot analysis of BTF3a/b expression in HeLa (A) and MCF7 (B) nuclear extracts.

BTF3a/b (A-5) - sc-166093 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BTF3a/b (A-5): sc-166093. Western blot analysis of BTF3a/b expression in HeLa (A) and MCF7 (B) nuclear extracts.

Anti-BTF3 antibody - ab107213 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BTF3 antibody (ab107213) at 1/100 dilution + A549 cell line lysates at 35 µg

Anti-BTF3 antibody - ab113974 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma (left) and human prostate carcinoma (right) tissues labelling BTF3 with ab113974 at 1/1000 (1µg/ml). Detection: DAB.

Anti-BTF3 antibody [628C5a] - ab50825 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 628C5a

Anti-BTF3 antibody - C-terminal - ab71420 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-BTF3 antibody - C-terminal (ab71420) at 1/60 dilution + K562 cell line lysate at 35 µg

Anti-BTF3 Antibody (C-Terminus) - LS-C20971 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody - LS-C77317 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-BTF3 Antibody (aa2-162) - LS-C125212 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BTF3 Antibody (C-Terminus) - LS-C31531 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-BTF3 Antibody - LS-C211742 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (HRP) - LS-C211743 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (FITC) - LS-C211745 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (Biotin) - LS-C211748 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, AP) - LS-C212967 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, APC) - LS-C212968 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, Biotin) - LS-C212969 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, FITC) - LS-C212970 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, Azide-free, HRP) - LS-C212971 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-35) - LS-C289067 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BTF3 Antibody (aa1-30, PE) - LS-C212972 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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