BTF3

Gene Symbol	BTF3
Entrez Gene	689
Alt Symbol	BETA-NAC, BTF3a, BTF3b, NACB
Species	Human
Gene Type	protein-coding
Description	basic transcription factor 3
Other Description	NAC-beta|RNA polymerase B transcription factor 3|nascent polypeptide-associated complex subunit beta|nascent-polypeptide-associated complex beta polypeptide|transcription factor BTF3
Swissprots	A8K510 Q76M56 Q13893 P20290
Accessions	AAA58398 EAW95723 EAW95724 EAW95725 EAW95726 EAW95727 EAW95728 P20290 AB062126 BAB93458 AK225964 AK291125 BAF83814 AK310919 BC008062 AAH08062 BC061913 BG182166 BT007120 AAP35784 BU661989 BX359147 DQ892976 ABM83902 DQ896224 ABM87223 X53280 CAA37375 X74070 CAA52200 NM_001037637 NP_001032726 NM_001207 NP_001198
Function	When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. {ECO:0000269|PubMed:10982809}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:10982809}. Nucleus {ECO:0000269|PubMed:10982809}. Note=The heterodimer with NACA is cytoplasmic.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

BTF3a/b CRISPR/Cas9 KO Plasmid (h) - sc-403520 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b HDR Plasmid (h) - sc-403520-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b Double Nickase Plasmid (h) - sc-403520-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b Double Nickase Plasmid (h2) - sc-403520-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b CRISPR Activation Plasmid (h) - sc-403520-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b CRISPR Activation Plasmid (h2) - sc-403520-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b Lentiviral Activation Particles (h) - sc-403520-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b Lentiviral Activation Particles (h2) - sc-403520-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

BTF3a/b siRNA (h) - sc-38513 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BTF3a shRNA Plasmid (h) - sc-38513-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BTF3a shRNA (h) Lentiviral Particles - sc-38513-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

BTF3 RNAi - H00000689-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU115491 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4100 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4100 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03542 from Sigma-Aldrich Category miRNA

BTF3 siRNA (Human) - CRH0481 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BTF3 - MBS8215919 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human Btf3 (NM_001207.4) - SHH248218 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human BTF3(NM_001037637.1) - SHG107129 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human BTF3(NM_001207.4) - SHG107147 from Creative biogene Category siRNA Species Reactivities Human

Human BTF3 siRNA - orb260983 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

BTF3 shRNA Plasmid (Human) - CHH0481 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

BTF3 miRNA 3'UTR clone - MiUTR1H-00977 from Creative biogene Species Reactivities Human

BTF3 miRNA 3'UTR clone - MiUTR1H-00978 from Creative biogene Species Reactivities Human

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