| Gene Symbol |
NPR2
|
| Entrez Gene |
4882
|
| Alt Symbol |
AMDM, ANPRB, ANPb, ECDM, GUC2B, GUCY2B, NPRB, NPRBi
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
natriuretic peptide receptor 2
|
| Other Description |
ANP-B|ANPR-B|GC-B|NPR-B|atrial natriuretic peptide B-type receptor|atrial natriuretic peptide receptor 2|atrial natriuretic peptide receptor type B|guanylate cyclase B|natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
|
| Swissprots |
Q4VAK7 B0ZBF2 B0ZBF3 Q8TA93 Q5TCV2 O60871 D3DRP3 D3DRP4 Q9UQ50 P20594
|
| Accessions |
AAS20319 ACA05920 ACA05921 ACA05922 BAA81737 EAW58337 EAW58338 EAW58339 EAW58340 P20594 AJ005282 CAA06466 BC023017 AAH23017 BC166642 AAI66642 BQ446138 HG501990 HG501991 L13436 XM_005251478 XP_005251535 XM_005251479 XP_005251536 XM_006716778 XP_006716841 XM_011517889 XP_011516191 XM_011517890 XP_011516192 XM_011517891 XP_011516193 XM_011517892 XP_011516194 XM_011517893 XP_011516195 XM_011517894 XP_011516196 XM_011517895 XP_011516197 NM_003995 NP_003986 NM_000907
|
| Function |
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. {ECO:0000269|PubMed:15146390, ECO:0000269|PubMed:1672777}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, Purine metabolism
|
![Western Blot: Natriuretic Peptide Receptor B Overexpression Lysate (Adult Normal) [NBP2-10563] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Natriuretic Peptide Receptor B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2255_Natriuretic%2520Peptide%2520Receptor%2520B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10563-img0001.jpg)