| Gene Symbol |
HCLS1
|
| Entrez Gene |
3059
|
| Alt Symbol |
CTTNL, HS1, lckBP1, p75
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hematopoietic cell-specific Lyn substrate 1
|
| Other Description |
hematopoietic lineage cell-specific protein
|
| Swissprots |
B4DQ69 Q6IBK9 Q9UDK0 Q53Y93 P14317
|
| Accessions |
EAW79505 EAW79506 P14317 AI091876 AK124015 AK225633 AK298663 BAG60831 AK298696 BAG60854 AK300301 BAG62054 AK312750 BAG35617 BC016758 AAH16758 BP338037 BQ002360 BT006824 AAP35470 BY994733 CA447092 CR456794 CAG33075 DC407066 DC427610 DQ890664 ABM81590 DQ893844 ABM84770 X16663 CAA34651 NM_001292041 NP_001278970 NM_005335 NP_005326
|
| Function |
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:7682714}; Peripheral membrane protein {ECO:0000269|PubMed:7682714}. Cytoplasm {ECO:0000269|PubMed:7682714}. Mitochondrion {ECO:0000305|PubMed:7682714}.
|
| Tissue Specificity |
Expressed only in tissues and cells of hematopoietic origin.
|
| Top Pathways |
Tight junction, Pathogenic Escherichia coli infection, Bacterial invasion of epithelial cells, Proteoglycans in cancer
|
