HCLS1

Gene Symbol	HCLS1
Entrez Gene	3059
Alt Symbol	CTTNL, HS1, lckBP1, p75
Species	Human
Gene Type	protein-coding
Description	hematopoietic cell-specific Lyn substrate 1
Other Description	hematopoietic lineage cell-specific protein
Swissprots	B4DQ69 Q6IBK9 Q9UDK0 Q53Y93 P14317
Accessions	EAW79505 EAW79506 P14317 AI091876 AK124015 AK225633 AK298663 BAG60831 AK298696 BAG60854 AK300301 BAG62054 AK312750 BAG35617 BC016758 AAH16758 BP338037 BQ002360 BT006824 AAP35470 BY994733 CA447092 CR456794 CAG33075 DC407066 DC427610 DQ890664 ABM81590 DQ893844 ABM84770 X16663 CAA34651 NM_001292041 NP_001278970 NM_005335 NP_005326
Function	Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Subcellular Location	Membrane {ECO:0000269|PubMed:7682714}; Peripheral membrane protein {ECO:0000269|PubMed:7682714}. Cytoplasm {ECO:0000269|PubMed:7682714}. Mitochondrion {ECO:0000305|PubMed:7682714}.
Tissue Specificity	Expressed only in tissues and cells of hematopoietic origin.
Top Pathways	Tight junction, Pathogenic Escherichia coli infection, Bacterial invasion of epithelial cells, Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Lck BP-1 CRISPR/Cas9 KO Plasmid (h) - sc-410540 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 HDR Plasmid (h) - sc-410540-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 Double Nickase Plasmid (h) - sc-410540-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 Double Nickase Plasmid (h2) - sc-410540-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 CRISPR Activation Plasmid (h) - sc-410540-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 CRISPR Activation Plasmid (h2) - sc-410540-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 Lentiviral Activation Particles (h) - sc-410540-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 Lentiviral Activation Particles (h2) - sc-410540-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Lck BP-1 siRNA (h) - sc-35800 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Lck BP-1 shRNA Plasmid (h) - sc-35800-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Lck BP-1 shRNA (h) Lentiviral Particles - sc-35800-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HCLS1 RNAi - H00003059-R01V from Novus Biologicals Category siRNA Prices $629.00 Sizes 20 nmol Species Reactivities Human

HCLS1 RNAi - H00003059-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU048281 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9923 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9923 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04064 from Sigma-Aldrich Category miRNA

HCLS1 siRNA (Human) - CRH2081 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HCLS1 - MBS8208373 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human HCLS1 (NM_005335.4) - SHH310809 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human HCLS1(NM_005335.4) - SHH115589 from Creative biogene Category siRNA Species Reactivities Human

Human HCLS1 siRNA - orb262583 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HCLS1 shRNA Plasmid (Human) - CHH2081 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

HCLS1 miRNA 3'UTR clone - MiUTR1H-04408 from Creative biogene Species Reactivities Human

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