PINX1

Gene Symbol	PINX1
Entrez Gene	54984
Alt Symbol	LPTL, LPTS
Species	Human
Gene Type	protein-coding
Description	PIN2/TERF1 interacting, telomerase inhibitor 1
Other Description	67-11-3 protein|PIN2 interacting protein 1|PIN2-interacting protein 1|PIN2/TERF1-interacting telomerase inhibitor 1|TRF1-interacting protein 1|hepatocellular carcinoma-related putative tumor suppressor|liver-related putative tumor suppressor|pin2-interacting protein X1|protein 67-11-3
Swissprots	Q9NWW2 Q6QWG9 Q548A5 Q96BK5 Q9HBU7 Q96QD7 Q7Z7J8 B2R9B1
Accessions	AAP12532 EAW65595 EAW65596 EAW65597 Q96BK5 AF205718 AAG18009 AF418553 AAN31333 AJ344104 CAC51436 AK313715 BAG36458 AY238941 AAP37006 AY523566 AAS19507 BC015479 AAH15479 BC043573 BC093762 AAH93762 BC143382 CB125276 NM_001284356 NP_001271285 NM_017884 NP_060354
Function	Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. {ECO:0000269|PubMed:15381700, ECO:0000269|PubMed:17198684, ECO:0000269|PubMed:19117989, ECO:0000269|PubMed:19265708, ECO:0000269|PubMed:19393617, ECO:0000269|PubMed:19553660}.
Subcellular Location	Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Note=Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE.
Tissue Specificity	Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PINX1 full length protein - ab85338 from Abcam Category Protein Source E. coli Species Human

Human PINX1 peptide - ab22903 from Abcam Category Peptide Species Human

PINX1 Antibody Blocking Peptide - LS-E25307 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PINX1 Antibody Blocking Peptide - LS-E27222 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PINX1 Antibody Blocking Peptide - LS-E20803 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PINX1 Antibody Blocking Peptide - LS-E20802 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PINX1 Partial Recombinant Protein - H00054984-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human PINX1 Protein - NBC1-26375 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

PINX1 Recombinant Protein - P3534 from Novus Biologicals Category Protein Prices $669.00 Sizes 100 µg Species Human

PINX1-Antibody-Center-Blocking-Peptide - BP9227c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PINX1 (aa225-237) blocking peptide - GTX88230-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

PINX1 blocking peptide - GTX89938-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

PINX1 Protein (OPPA02218) - OPPA02218 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human PINX1 protein - orb81277 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Goat anti PINX1 antibody Immunizing peptide - orb16477 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PINX1 Immunizing peptide - orb17661 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PINX1 Blocking Peptide - 33R-2516 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PINX1 Blocking Peptide - 33R-2507 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PINX1 protein (His tag) - 80R-1144 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

PINX1 Peptide - AC21-0135-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PINX1 Peptide - AC21-2043-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PINX1 (1-328, His-tag) - AR09191PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 500 µg Source E. coli Species Human

PINX1 (1-328, His-tag) - AR09191PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 100 µg Source E. coli Species Human

PINX1 - H00054984-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PINX1 - H00054984-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Search more