Gene Symbol | KCTD13 |
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Entrez Gene | 253980 |
Alt Symbol | BACURD1, FKSG86, PDIP1, POLDIP1, hBACURD1 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel tetramerization domain containing 13 |
Other Description | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1|BTB/POZ domain-containing protein KCTD13|TNFAIP1-like protein|polymerase delta-interacting protein 1|potassium channel tetramerisation domain containing 13 |
Swissprots | Q96P93 A8K0R5 Q8WZ19 Q96SA1 |
Accessions | EAW79969 EAW79970 Q8WZ19 AF289573 AAL55757 AF401315 AAL14962 AK097407 AK289630 BAF82319 AY027918 AAK27301 BC036228 AAH36228 BI553707 DQ891555 ABM82481 DQ894742 ABM85668 XM_011545783 XP_011544085 XM_011545784 XP_011544086 XR_950767 XR_950768 NM_178863 NP_849194 NR_110933 |
Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. {ECO:0000269|PubMed:19782033}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11593007}. |
Tissue Specificity | Expressed in a wide variety of tissues. {ECO:0000269|PubMed:11593007}. |
POLDIP1 protein (His-DHFR tag) - ab127506 from Abcam
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KCTD13 Antibody Blocking Peptide - LS-E4980 from LifeSpan Bioscience
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KCTD13 Antibody Blocking Peptide - LS-E12638 from LifeSpan Bioscience
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POLDIP1 Partial Recombinant Protein - H00253980-Q01 from Novus Biologicals
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KCTD13-Antibody-C-term-Blocking-Peptide - BP17375b from Abgent, a WuXi AppTec company
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KCTD13 Blocking Peptide - 33R-7119 from Fitzgerald
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KCTD13 - H00253980-Q01-10 from Acris Antibodies
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KCTD13 - H00253980-Q01-25 from Acris Antibodies
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KCTD13 fusion protein - Ag3835 from Proteintech Group
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Recombinant Human KCTD13, His-tagged - KCTD13-292H from Creative Biomart
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Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1(KCTD13) - CSB-YP820186HU CSB-EP820186HU CSB-BP820186HU CSB-MP820186HU from Cusabio
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KCTD13 (full length, N-term HIS tag) - TP760326 from Acris Antibodies
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POLDIP1 Recombinant Protein Antigen - NBP2-14147PEP from Novus Biologicals
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KCTD13 Peptide, Human - M34GP08017H from Creative Peptides
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BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (KCTD13), Recombinant Protein - MBS1301457 from MyBioSource
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