Gene Symbol | KATNB1 |
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Entrez Gene | 10300 |
Alt Symbol | KAT, LIS6 |
Species | Human |
Gene Type | protein-coding |
Description | katanin p80 (WD repeat containing) subunit B 1 |
Other Description | katanin (80 kDa)|katanin p80 (WD40-containing) subunit B 1|katanin p80 WD40 repeat-containing subunit B1|katanin p80 WD40-containing subunit B1|katanin p80 subunit B1|p80 katanin |
Swissprots | A6NCG6 O60620 Q9BVA0 |
Accessions | EAW82950 EAW82951 EAW82952 Q9BVA0 AB209250 BAD92487 AF052432 AAC09328 BC001353 AAH01353 BT007022 AAP35668 BU501165 CA306372 CR456762 CAG33043 DQ890767 ABM81693 XM_005255772 XP_005255829 XM_006721121 XP_006721184 XM_006721122 XP_006721185 XM_006721123 XP_006721186 XM_011522810 XP_011521112 NM_005886 NP_005877 |
Function | Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth. {ECO:0000255|HAMAP-Rule:MF_03022}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles. |
Katanin p80 B1 (C-12) - sc-107229 from Santa Cruz Biotechnology
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Katanin p80 B1 (C-4) - sc-377226 from Santa Cruz Biotechnology
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Katanin p80 B1 (H-300) - sc-292216 from Santa Cruz Biotechnology
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Katanin p80 B1 (K-17) - sc-107230 from Santa Cruz Biotechnology
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Anti-katanin p80 antibody - ab118219 from Abcam
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Anti-Katanin p80 antibody [SPM274] - ab125279 from Abcam
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Anti-KATNB1 Antibody (clone 4C10) - LS-C173438 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 3B6) - LS-C173449 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa429-578) - LS-C178677 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5A10) - LS-C173450 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 1A3) - LS-C340597 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5F9) - LS-C173451 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5E1) - LS-C173455 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5C4) - LS-C173437 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359) - LS-C165401 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5H6) - LS-C173406 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, AP) - LS-C260807 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, APC) - LS-C260808 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, Biotin) - LS-C260809 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, FITC) - LS-C260810 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5A6) - LS-C173407 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (clone 5A1) - LS-C173102 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, Azide-free, HRP) - LS-C260811 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa331-359, PE) - LS-C260812 from LifeSpan Bioscience
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Anti-KATNB1 Antibody (aa330-359) - LS-C322358 from LifeSpan Bioscience
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