VNN1

Gene Symbol	VNN1
Entrez Gene	8876
Alt Symbol	HDLCQ8, Tiff66
Species	Human
Gene Type	protein-coding
Description	vanin 1
Other Description	pantetheinase\|pantetheine hydrolase\|vanin-1\|vannin 1\|vascular non-inflammatory molecule 1
Swissprots	O95497 Q4VAS8 Q4JFW6 Q4VAS7 A8K310 Q4VAS9 Q9UJF4 Q9UF16
Accessions	AAY88742 EAW48020 O95497 AJ132099 CAA10568 AK095461 AK290425 BAF83114 AK314265 BAG36929 BC096265 AAH96265 BC096266 AAH96266 BC096267 AAH96267 BC096268 AAH96268 BJ995136 U39664 AAF21453 NM_004666 NP_004657
Function	Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. {ECO:0000269\|PubMed:10567687, ECO:0000269\|PubMed:11491533}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.
Tissue Specificity	Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin. {ECO:0000269\|PubMed:19322213}.
Top Pathways	Pantothenate and CoA biosynthesis

vanin-1 (H-73) - sc-367370 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

vanin-1 (N-20) - sc-16776 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

vanin-1 (C-20) - sc-16778 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

vanin-1 (C-20): sc-16778. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing apical membrane and cytoplasmic staining of cells in tubules.

vanin-1 (3-RE8) - sc-135599 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

vanin-1 (3-RE8): sc-135599. Western blot analysis of vanin-1 expression in A-431 whole cell lysate.

Anti-VNN1 antibody - ab96171 from Abcam

Prices	$378.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 antibody (ab96171) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

Anti-VNN1 antibody - ab69844 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-VNN1 Antibody (aa389-497, Biotin) - LS-C300086 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa390-503, Biotin) - LS-C297104 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa229-379, Biotin) - LS-C300134 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa36-223, Biotin) - LS-C300163 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa229-379, FITC) - LS-C302052 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa390-503, FITC) - LS-C303860 from LifeSpan Bioscience

Prices	$465.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa36-223, FITC) - LS-C304466 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa389-497, FITC) - LS-C304647 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa232-457) - LS-C186354 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. vanin-1 antibody. VNN1 antibody diluted at 1:1000.

Anti-VNN1 Antibody (aa389-497) - LS-C296939 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa229-379) - LS-C296938 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (clone 4E11) - LS-C139167 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal
Clone	4E11

Detection limit for recombinant GST tagged VNN1 is 1 ng/ml as a capture antibody.

Anti-VNN1 Antibody (aa390-503) - LS-C296937 from LifeSpan Bioscience

Prices	$415.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody (aa36-223) - LS-C296936 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-VNN1 Antibody - LS-C332505 from LifeSpan Bioscience

Prices	$305.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using VNN1 antibody.

Vanin-1/VNN1 Antibody - H00008876-D01 from Novus Biologicals

Prices	$399.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunoprecipitation: VNN1 Antibody [H00008876-D01] - Transfected lysate using anti-VNN1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with VNN1 purified MaxPab mouse polyclonal antibody.

Vanin-1/VNN1 Antibody - NBP2-38044 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: Vanin-1/VNN1 Antibody [NBP2-38044] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

Vanin-1/VNN1 Antibody - H00008876-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Vanin-1/VNN1 Antibody (2B10) - H00008876-M05 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B10

ELISA: VNN1 Antibody (2B10) [H00008876-M05] - Detection limit for recombinant GST tagged VNN1 is approximately 0.1ng/ml as a capture antibody.

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