Gene Symbol | VNN1 |
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Entrez Gene | 8876 |
Alt Symbol | HDLCQ8, Tiff66 |
Species | Human |
Gene Type | protein-coding |
Description | vanin 1 |
Other Description | pantetheinase|pantetheine hydrolase|vanin-1|vannin 1|vascular non-inflammatory molecule 1 |
Swissprots | O95497 Q4VAS8 Q4JFW6 Q4VAS7 A8K310 Q4VAS9 Q9UJF4 Q9UF16 |
Accessions | AAY88742 EAW48020 O95497 AJ132099 CAA10568 AK095461 AK290425 BAF83114 AK314265 BAG36929 BC096265 AAH96265 BC096266 AAH96266 BC096267 AAH96267 BC096268 AAH96268 BJ995136 U39664 AAF21453 NM_004666 NP_004657 |
Function | Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. {ECO:0000269|PubMed:10567687, ECO:0000269|PubMed:11491533}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. |
Tissue Specificity | Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin. {ECO:0000269|PubMed:19322213}. |
Top Pathways | Pantothenate and CoA biosynthesis |
VNN1 293T Cell Transient Overexpression Lysate(Denatured) - H00008876-T01 from Acris Antibodies
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VNN1 overexpression lysate - LY401479 from Acris Antibodies
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VNN1 293 Cell Lysate - 401344 from ABBIOTEC
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Vanin-1/VNN1 Overexpression Lysate (Denatured) - H00008876-T01 from Novus Biologicals
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Vanin-1/VNN1 Overexpression Lysate (Native) - NBL1-17732 from Novus Biologicals
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VNN1 Over-expression Lysate Product - GWB-C0DD74 from Genway Biotech
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Human VNN1 / Vanin-1 HEK293 Cell Lysate (WB positive control) - 11662-H08HL-300 from Sino Biological
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Human VNN1 Human Cells Transfected Lysate (positive control) (denatured) - orb173384 from Biorbyt
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Vanin-1/VNN1 Overexpression Lysate (Denatured) - H00008876-T02 from Novus Biologicals
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Panoply™ Human VNN1 Knockdown Stable Cell Line - CSC-DC017296 from Creative biogene
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