Gene Symbol | B3GNT2 |
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Entrez Gene | 10678 |
Alt Symbol | B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2 |
Species | Human |
Gene Type | protein-coding |
Description | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
Other Description | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2|UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1|beta-1,3-Gn-T1|beta-1,3-Gn-T2|beta-1,3-N-acetylglucosaminyltransferase bGnT-1|beta-1,3-N-acetylglucosaminyltransferase bGnT-2|beta3Gn-T1|beta3Gn-T2 |
Swissprots | Q9NY97 Q9NQQ9 Q54AC1 Q9NQR0 Q9NUT9 |
Accessions | AAX93271 EAW99977 EAW99978 EAW99979 EAW99980 Q9NY97 AB049584 BAB21530 AF092051 AAD09764 AF288208 AAF97253 AF288209 AAF97254 AJ006077 CAB91546 AK002009 BAA92031 BC030579 AAH30579 BC047933 AAH47933 HQ447202 ADQ31689 XM_011532486 XP_011530788 NM_006577 NP_006568 NM_033252 |
Function | Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase. {ECO:0000269|PubMed:11042166, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:9892646}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11042166}. |
Top Pathways | Glycosaminoglycan biosynthesis - keratan sulfate, Glycosphingolipid biosynthesis - lacto and neolacto series |
β3Gn-T2 (C-14) - sc-160947 from Santa Cruz Biotechnology
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β3Gn-T2 (8G8) - sc-134231 from Santa Cruz Biotechnology
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β3Gn-T2 (P-13) - sc-160948 from Santa Cruz Biotechnology
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Anti-B3GNT1 antibody - ab77561 from Abcam
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Anti-B3GNT1 antibody - ab56960 from Abcam
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Anti-B3GNT2 Antibody (clone 4B9) - LS-C337857 from LifeSpan Bioscience
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Anti-B3GNT2 Antibody (aa111-210) - LS-C306471 from LifeSpan Bioscience
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Anti-B3GNT2 Antibody (aa29-397) - LS-C189773 from LifeSpan Bioscience
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Anti-B3GNT2 Antibody (aa348-359) - LS-C61710 from LifeSpan Bioscience
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Anti-B3GNT2 Antibody (clone 1G10) - LS-C174258 from LifeSpan Bioscience
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Anti-B3GNT2 Antibody (clone 3A9) - LS-C174261 from LifeSpan Bioscience
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody - AF3960 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody (485327) - MAB3960 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody - NBP1-88951 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody (1A8) - H00010678-M05 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody - NBP1-00158 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody - NBP1-31915 from Novus Biologicals
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Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibody - H00010678-A01 from Novus Biologicals
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Anti-B3GNT2 antibody produced in rabbit - HPA005997 from Sigma-Aldrich
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Monoclonal Anti-B3GNT1 antibody produced in mouse - WH0010678M5 from Sigma-Aldrich
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B3GNT1-Antibody-monoclonal-M05 - AT1254a from Abgent, a WuXi AppTec company
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B3GNT2-Antibody - AF1131a from Abgent, a WuXi AppTec company
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Anti -B3GNT2 (B3GN-T2, B3GNT-2, UDP-GlcNAc:betaGalbeta-1,3-N-acetylglucosaminyltransferase 2, B3GN-T1, B3GNT, B3GNT1, BETA3GNT, B3GALT7) - A0528-19G1 from USBiological Life Science
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Anti -B3GNT2 (B3GNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,B3GN-T1, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT) - A0528-19G from USBiological Life Science
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Anti -B3GNT2 (B3GNT2, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,B3GN-T1, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT) (AP) - A0528-19G-AP from USBiological Life Science
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